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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Hypoxia-Inducible Factor-1α Target Genes Contribute to Retinal Neuroprotection
|
|---|---|
| Published in |
Frontiers in Cellular Neuroscience, February 2017
|
| DOI | 10.3389/fncel.2017.00020 |
| Pubmed ID | |
| Authors |
Lin Cheng, Honghua Yu, Naihong Yan, Kunbei Lai, Mengqing Xiang |
| Abstract |
Hypoxia-inducible factor (HIF) is a transcription factor that facilitates cellular adaptation to hypoxia and ischemia. Long-standing evidence suggests that one isotype of HIF, HIF-1α, is involved in the pathogenesis of various solid tumors and cardiac diseases. However, the role of HIF-1α in retina remains poorly understood. HIF-1α has been recognized as neuroprotective in cerebral ischemia in the past two decades. Additionally, an increasing number of studies has shown that HIF-1α and its target genes contribute to retinal neuroprotection. This review will focus on recent advances in the studies of HIF-1α and its target genes that contribute to retinal neuroprotection. A thorough understanding of the function of HIF-1α and its target genes may lead to identification of novel therapeutic targets for treating degenerative retinal diseases including glaucoma, age-related macular degeneration, diabetic retinopathy, and retinal vein occlusions. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 86 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 86 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 14 | 16% |
| Student > Ph. D. Student | 13 | 15% |
| Researcher | 10 | 12% |
| Student > Master | 7 | 8% |
| Professor > Associate Professor | 4 | 5% |
| Other | 10 | 12% |
| Unknown | 28 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 17 | 20% |
| Medicine and Dentistry | 15 | 17% |
| Agricultural and Biological Sciences | 10 | 12% |
| Neuroscience | 6 | 7% |
| Engineering | 2 | 2% |
| Other | 4 | 5% |
| Unknown | 32 | 37% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 March 2017.
All research outputs
#20,407,586
of 22,957,478 outputs
Outputs from Frontiers in Cellular Neuroscience
#3,587
of 4,259 outputs
Outputs of similar age
#271,844
of 312,054 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#77
of 96 outputs
Altmetric has tracked 22,957,478 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,259 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 312,054 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 96 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.