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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Limitations of Sulforhodamine 101 for Brain Imaging
|
|---|---|
| Published in |
Frontiers in Cellular Neuroscience, February 2017
|
| DOI | 10.3389/fncel.2017.00044 |
| Pubmed ID | |
| Authors |
Swen Hülsmann, Liya Hagos, Heike Heuer, Christian Schnell |
| Abstract |
Since 2004, the red fluorescent dye Sulforhodamine 101 (SR101) has been boosting the functional analysis of astrocytes in a functional environment in an unprecedented way. However, two major limitations have been challenging the usefulness of this tool for cellular imaging: (i) SR101 is not as specific for astrocytes as previously reported; and (ii) discoveries of severe excitatory side effects of SR101 are bearing the risk of unwanted alteration of the system of interest. In this article, we summarize the current knowledge about SR101-labeling protocols and discuss the problems that arise from varying of the staining protocols. Furthermore, we provide a testable hypothesis for the observed hyper-excitability that can be observed when using SR101. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 83 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 83 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 19 | 23% |
| Researcher | 14 | 17% |
| Student > Doctoral Student | 9 | 11% |
| Student > Master | 9 | 11% |
| Student > Bachelor | 6 | 7% |
| Other | 9 | 11% |
| Unknown | 17 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 36 | 43% |
| Biochemistry, Genetics and Molecular Biology | 7 | 8% |
| Agricultural and Biological Sciences | 7 | 8% |
| Engineering | 3 | 4% |
| Medicine and Dentistry | 3 | 4% |
| Other | 5 | 6% |
| Unknown | 22 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 August 2021.
All research outputs
#17,881,664
of 22,958,253 outputs
Outputs from Frontiers in Cellular Neuroscience
#2,946
of 4,259 outputs
Outputs of similar age
#223,974
of 310,855 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#54
of 95 outputs
Altmetric has tracked 22,958,253 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,259 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one is in the 23rd percentile – i.e., 23% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 310,855 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 95 others from the same source and published within six weeks on either side of this one. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.