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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Energy Homeostasis and Abnormal RNA Metabolism in Amyotrophic Lateral Sclerosis
|
|---|---|
| Published in |
Frontiers in Cellular Neuroscience, May 2017
|
| DOI | 10.3389/fncel.2017.00126 |
| Pubmed ID | |
| Authors |
Yu-Ju Liu, Po-Yi Tsai, Yijuang Chern |
| Abstract |
Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease that is clinically characterized by progressive muscle weakness and impaired voluntary movement due to the loss of motor neurons in the brain, brain stem and spinal cord. To date, no effective treatment is available. Ample evidence suggests that impaired RNA homeostasis and abnormal energy status are two major pathogenesis pathways in ALS. In the present review article, we focus on recent studies that report molecular insights of both pathways, and discuss the possibility that energy dysfunction might negatively regulate RNA homeostasis via the impairment of cytoplasmic-nuclear shuttling in motor neurons and subsequently contribute to the development of ALS. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Chile | 1 | 25% |
| Unknown | 3 | 75% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Scientists | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Korea, Republic of | 1 | 3% |
| Unknown | 38 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 10 | 26% |
| Student > Ph. D. Student | 8 | 21% |
| Student > Doctoral Student | 4 | 10% |
| Professor | 2 | 5% |
| Researcher | 2 | 5% |
| Other | 3 | 8% |
| Unknown | 10 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 9 | 23% |
| Biochemistry, Genetics and Molecular Biology | 8 | 21% |
| Agricultural and Biological Sciences | 5 | 13% |
| Medicine and Dentistry | 4 | 10% |
| Mathematics | 1 | 3% |
| Other | 1 | 3% |
| Unknown | 11 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 May 2017.
All research outputs
#2,674,873
of 22,971,207 outputs
Outputs from Frontiers in Cellular Neuroscience
#459
of 4,261 outputs
Outputs of similar age
#50,960
of 310,942 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#8
of 95 outputs
Altmetric has tracked 22,971,207 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,261 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 310,942 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 95 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 91% of its contemporaries.