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Attention Score in Context
| Title |
Effects of Voluntary Wheel-Running Types on Hippocampal Neurogenesis and Spatial Cognition in Middle-Aged Mice
|
|---|---|
| Published in |
Frontiers in Cellular Neuroscience, June 2018
|
| DOI | 10.3389/fncel.2018.00177 |
| Pubmed ID | |
| Authors |
Yi-Qing Huang, Cheng Wu, Xiao-Fei He, Dan Wu, Xia He, Feng-Yin Liang, Guang-Yan Dai, Zhong Pei, Guang-Qing Xu, Yue Lan |
| Abstract |
While increasing evidence demonstrated that voluntary wheel running promotes cognitive function, little is known on how different types of voluntary wheel running affect cognitive function in elderly populations. We investigated the effects of various voluntary wheel-running types on adult hippocampal neurogenesis and spatial cognition in middle-aged mice. Male C57BL6 and Thy1-green fluorescent protein (GFP) transgenic mice (13 months) were equally assigned to one of the following groups: (1) T1: no voluntary wheel running; (2) T2: intermittent voluntary wheel running; and (3) T3: continuous voluntary wheel running. The Thy1-GFP transgenic mice were used to specifically label granule cells, since Thy-1 is a promoter for neuronal expression. Behavioral evaluations suggested that intermittent voluntary wheel running improved Morris water maze performance in middle-aged mice. The number of BrdU-positive cells was significantly higher in both intermittent and continuous voluntary wheel running compared with no voluntary wheel running. However, only intermittent voluntary wheel running facilitated the newborn cells to differentiate into granule cells, while newborn cells tended to differentiate into astrocytes and repopulation of microglia was also enhanced in the continuous voluntary wheel-running group. These results indicated that intermittent voluntary exercise may be more beneficial for enhancing spatial memory. Effective improvement of hippocampal neurogenesis was also caused by intermittent voluntary wheel running in middle-aged mice. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 63 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 11 | 17% |
| Student > Master | 10 | 16% |
| Student > Ph. D. Student | 8 | 13% |
| Researcher | 5 | 8% |
| Professor | 3 | 5% |
| Other | 11 | 17% |
| Unknown | 15 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 20 | 32% |
| Medicine and Dentistry | 7 | 11% |
| Agricultural and Biological Sciences | 5 | 8% |
| Psychology | 5 | 8% |
| Biochemistry, Genetics and Molecular Biology | 2 | 3% |
| Other | 5 | 8% |
| Unknown | 19 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 July 2018.
All research outputs
#17,981,442
of 23,092,602 outputs
Outputs from Frontiers in Cellular Neuroscience
#2,967
of 4,279 outputs
Outputs of similar age
#237,937
of 329,076 outputs
Outputs of similar age from Frontiers in Cellular Neuroscience
#80
of 115 outputs
Altmetric has tracked 23,092,602 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,279 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one is in the 23rd percentile – i.e., 23% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 329,076 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 115 others from the same source and published within six weeks on either side of this one. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.