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Mendeley readers
Attention Score in Context
| Title |
Retrogradely Transportable Lentivirus Tracers for Mapping Spinal Cord Locomotor Circuits
|
|---|---|
| Published in |
Frontiers in Neural Circuits, July 2018
|
| DOI | 10.3389/fncir.2018.00060 |
| Pubmed ID | |
| Authors |
Imran S. Sheikh, Kathleen M. Keefe, Noelle A. Sterling, Ian P. Junker, Chidubem I. Eneanya, Yingpeng Liu, Xiao-Qing Tang, George M. Smith |
| Abstract |
Retrograde tracing is a key facet of neuroanatomical studies involving long distance projection neurons. Previous groups have utilized a variety of tools ranging from classical chemical tracers to newer methods employing viruses for gene delivery. Here, we highlight the usage of a lentivirus that permits highly efficient retrograde transport (HiRet) from synaptic terminals within the cervical and lumbar enlargements of the spinal cord. By injecting HiRet, we can clearly identify supraspinal and propriospinal circuits innervating motor neuron pools relating to forelimb and hindlimb function. We observed robust labeling of propriospinal neurons, including high fidelity details of dendritic arbors and axon terminals seldom seen with chemical tracers. In addition, we examine changes in interneuronal circuits occurring after a thoracic contusion, highlighting populations that potentially contribute to spontaneous behavioral recovery in this lesion model. Our study demonstrates that the HiRet lentivirus is a unique tool for examining neuronal circuitry within the brain and spinal cord. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 33% |
| Switzerland | 1 | 33% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Scientists | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 44 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 7 | 16% |
| Student > Ph. D. Student | 7 | 16% |
| Student > Master | 6 | 14% |
| Researcher | 6 | 14% |
| Professor > Associate Professor | 3 | 7% |
| Other | 4 | 9% |
| Unknown | 11 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 19 | 43% |
| Agricultural and Biological Sciences | 3 | 7% |
| Engineering | 3 | 7% |
| Environmental Science | 1 | 2% |
| Sports and Recreations | 1 | 2% |
| Other | 3 | 7% |
| Unknown | 14 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 August 2018.
All research outputs
#15,542,250
of 23,098,660 outputs
Outputs from Frontiers in Neural Circuits
#786
of 1,222 outputs
Outputs of similar age
#209,957
of 330,303 outputs
Outputs of similar age from Frontiers in Neural Circuits
#18
of 27 outputs
Altmetric has tracked 23,098,660 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,222 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 330,303 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.