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The Role of T-Type Calcium Channel Genes in Absence Seizures

Overview of attention for article published in Frontiers in Neurology, May 2014
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  • Good Attention Score compared to outputs of the same age and source (78th percentile)

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3 X users

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Title
The Role of T-Type Calcium Channel Genes in Absence Seizures
Published in
Frontiers in Neurology, May 2014
DOI 10.3389/fneur.2014.00045
Pubmed ID
Authors

Yucai Chen, William Davis Parker, Keling Wang

Abstract

The thalamic relay neurons, reticular thalamic nucleus, and neocortical pyramidal cells form a circuit that sustains oscillatory burst firing, and is regarded as the underlying mechanism of absence seizures. T-type calcium channels play a key role in this circuit. Here, we review the role of T-type calcium channel genes in the development of absence seizures, and emphasize gain or loss of function mutations, and other variations that alter both quantity and quality of transcripts, and methylation status of isoforms of T-type calcium channel proteins might be of equal importance in understanding the pathological mechanism of absence seizures.

X Demographics

X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 89 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Malta 1 1%
Unknown 87 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 18 20%
Researcher 12 13%
Student > Master 10 11%
Student > Ph. D. Student 7 8%
Professor 7 8%
Other 14 16%
Unknown 21 24%
Readers by discipline Count As %
Agricultural and Biological Sciences 16 18%
Medicine and Dentistry 14 16%
Neuroscience 14 16%
Biochemistry, Genetics and Molecular Biology 7 8%
Pharmacology, Toxicology and Pharmaceutical Science 7 8%
Other 9 10%
Unknown 22 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 December 2019.
All research outputs
#14,249,391
of 23,274,744 outputs
Outputs from Frontiers in Neurology
#5,588
of 12,176 outputs
Outputs of similar age
#118,978
of 228,559 outputs
Outputs of similar age from Frontiers in Neurology
#12
of 61 outputs
Altmetric has tracked 23,274,744 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 12,176 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.3. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 228,559 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 61 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 78% of its contemporaries.