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Epilepsy Mechanisms in Neurocutaneous Disorders: Tuberous Sclerosis Complex, Neurofibromatosis Type 1, and Sturge–Weber Syndrome

Overview of attention for article published in Frontiers in Neurology, March 2017
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (64th percentile)
  • Good Attention Score compared to outputs of the same age and source (67th percentile)

Mentioned by

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2 X users
facebook
1 Facebook page
wikipedia
3 Wikipedia pages

Citations

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50 Dimensions

Readers on

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82 Mendeley
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Title
Epilepsy Mechanisms in Neurocutaneous Disorders: Tuberous Sclerosis Complex, Neurofibromatosis Type 1, and Sturge–Weber Syndrome
Published in
Frontiers in Neurology, March 2017
DOI 10.3389/fneur.2017.00087
Pubmed ID
Authors

Carl E. Stafstrom, Verena Staedtke, Anne M. Comi

Abstract

Neurocutaneous disorders are multisystem diseases affecting skin, brain, and other organs. Epilepsy is very common in the neurocutaneous disorders, affecting up to 90% of patients with tuberous sclerosis complex (TSC) and Sturge-Weber syndrome (SWS), for example. The mechanisms underlying the increased predisposition to brain hyperexcitability differ between disorders, yet some molecular pathways overlap. For instance, the mechanistic target of rapamycin (mTOR) signaling cascade plays a central role in seizures and epileptogenesis in numerous acquired and genetic disorders, including several neurocutaneous disorders. Potential routes for target-specific treatments are emerging as the genetic and molecular pathways involved in neurocutaneous disorders become increasingly understood. This review explores the clinical features and mechanisms of epilepsy in three common neurocutaneous disorders-TSC, neurofibromatosis type 1, and SWS.

X Demographics

X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 82 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 82 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 14 17%
Student > Ph. D. Student 9 11%
Student > Postgraduate 8 10%
Student > Doctoral Student 7 9%
Student > Master 7 9%
Other 17 21%
Unknown 20 24%
Readers by discipline Count As %
Medicine and Dentistry 26 32%
Neuroscience 12 15%
Biochemistry, Genetics and Molecular Biology 8 10%
Agricultural and Biological Sciences 4 5%
Immunology and Microbiology 3 4%
Other 7 9%
Unknown 22 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 April 2023.
All research outputs
#6,661,686
of 23,539,593 outputs
Outputs from Frontiers in Neurology
#4,390
of 12,476 outputs
Outputs of similar age
#114,530
of 335,372 outputs
Outputs of similar age from Frontiers in Neurology
#47
of 147 outputs
Altmetric has tracked 23,539,593 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 12,476 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.4. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 335,372 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.
We're also able to compare this research output to 147 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.