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Blood Pressure and Penumbral Sustenance in Stroke from Large Vessel Occlusion

Overview of attention for article published in Frontiers in Neurology, July 2017
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  • Above-average Attention Score compared to outputs of the same age (61st percentile)
  • Good Attention Score compared to outputs of the same age and source (66th percentile)

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Title
Blood Pressure and Penumbral Sustenance in Stroke from Large Vessel Occlusion
Published in
Frontiers in Neurology, July 2017
DOI 10.3389/fneur.2017.00317
Pubmed ID
Authors

Robert W. Regenhardt, Alvin S. Das, Christopher J. Stapleton, Ronil V. Chandra, James D. Rabinov, Aman B. Patel, Joshua A. Hirsch, Thabele M. Leslie-Mazwi

Abstract

The global burden of stroke remains high, and of the various subtypes of stroke, large vessel occlusions (LVOs) account for the largest proportion of stroke-related death and disability. Several randomized controlled trials in 2015 changed the landscape of stroke care worldwide, with endovascular thrombectomy (ET) now the standard of care for all eligible patients. With the proven success of this therapy, there is a renewed focus on penumbral sustenance. In this review, we describe the ischemic penumbra, collateral circulation, autoregulation, and imaging assessment of the penumbra. Blood pressure goals in acute stroke remain controversial, and we review the current data and suggest an approach for induced hypertension in the acute treatment of patients with LVOs. Finally, in addition to reperfusion and enhanced perfusion, efforts focused on developing therapeutic targets that afford neuroprotection and augment neural repair will gain increasing importance. ET has revolutionized stroke care, and future emphasis will be placed on promoting penumbral sustenance, which will increase patient eligibility for this highly effective therapy and reduce overall stroke-related death and disability.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 95 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 95 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 14 15%
Student > Bachelor 14 15%
Other 11 12%
Student > Ph. D. Student 7 7%
Student > Master 7 7%
Other 20 21%
Unknown 22 23%
Readers by discipline Count As %
Medicine and Dentistry 34 36%
Neuroscience 10 11%
Biochemistry, Genetics and Molecular Biology 5 5%
Nursing and Health Professions 4 4%
Engineering 3 3%
Other 7 7%
Unknown 32 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 May 2018.
All research outputs
#8,714,812
of 26,080,956 outputs
Outputs from Frontiers in Neurology
#5,292
of 14,842 outputs
Outputs of similar age
#126,240
of 331,356 outputs
Outputs of similar age from Frontiers in Neurology
#66
of 199 outputs
Altmetric has tracked 26,080,956 research outputs across all sources so far. This one has received more attention than most of these and is in the 66th percentile.
So far Altmetric has tracked 14,842 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 331,356 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.
We're also able to compare this research output to 199 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.