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Immune Modulation in the Treatment of Amyotrophic Lateral Sclerosis: A Review of Clinical Trials

Overview of attention for article published in Frontiers in Neurology, September 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (84th percentile)
  • High Attention Score compared to outputs of the same age and source (87th percentile)

Mentioned by

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6 X users
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2 patents
wikipedia
1 Wikipedia page

Citations

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39 Dimensions

Readers on

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85 Mendeley
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Title
Immune Modulation in the Treatment of Amyotrophic Lateral Sclerosis: A Review of Clinical Trials
Published in
Frontiers in Neurology, September 2017
DOI 10.3389/fneur.2017.00486
Pubmed ID
Authors

Syed I. Khalid, Leonel Ampie, Ryan Kelly, Shafeeq S. Ladha, Christopher Dardis

Abstract

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by the degeneration of motor neurons. Though many molecular and genetic causes are thought to serve as predisposing or disease propagating factors, the underlying pathogenesis of the disease is not known. Recent discoveries have demonstrated the presence of inflammation propagating substrates in the central nervous system of patients afflicted with ALS. Over the past decade, this hypothesis has incited an effort to better understand the role of the immune system in ALS and has led to the trial of several potential immune-modulating therapies. Here, we briefly review advances in the role of such therapies. The clinical trials discussed here are currently ongoing or have been concluded at the time of writing.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 85 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 85 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 13%
Researcher 11 13%
Student > Bachelor 10 12%
Student > Master 10 12%
Student > Doctoral Student 7 8%
Other 19 22%
Unknown 17 20%
Readers by discipline Count As %
Medicine and Dentistry 12 14%
Neuroscience 12 14%
Biochemistry, Genetics and Molecular Biology 9 11%
Agricultural and Biological Sciences 9 11%
Pharmacology, Toxicology and Pharmaceutical Science 6 7%
Other 14 16%
Unknown 23 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 October 2023.
All research outputs
#2,732,987
of 24,784,213 outputs
Outputs from Frontiers in Neurology
#1,496
of 13,861 outputs
Outputs of similar age
#50,388
of 325,487 outputs
Outputs of similar age from Frontiers in Neurology
#27
of 202 outputs
Altmetric has tracked 24,784,213 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,861 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.4. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 325,487 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 202 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.