Title |
Therapeutic Inertia in the New Landscape of Multiple Sclerosis Care
|
---|---|
Published in |
Frontiers in Neurology, March 2018
|
DOI | 10.3389/fneur.2018.00174 |
Pubmed ID | |
Authors |
Gustavo Saposnik, Xavier Montalban |
Abstract |
The landscape of multiple sclerosis (MS) treatment is constantly changing. Significant heterogeneity exists in the efficacy and risks associated with these therapies. Therefore, clinicians have the challenge to tailor treatment based on several factors (disease activity level, risk of progression, individual patient preferences and characteristics, personal expertise, etc.), to identify the optimal balance between safety and efficacy. However, most clinicians have limited education in decision-making and formal training in risk management. Together, these factors may lead to therapeutic inertia (TI); defined as the absence of treatment initiation or intensification when therapeutic goals are unmet. TI may lead to suboptimal treatments choices, worse clinical outcomes, and more disability. This article provides a succinct overview on factors influencing TI in MS care. |
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Country | Count | As % |
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United States | 5 | 38% |
Canada | 1 | 8% |
Egypt | 1 | 8% |
Spain | 1 | 8% |
Unknown | 5 | 38% |
Demographic breakdown
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Practitioners (doctors, other healthcare professionals) | 3 | 23% |
Scientists | 1 | 8% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 34 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Other | 8 | 24% |
Student > Ph. D. Student | 4 | 12% |
Researcher | 4 | 12% |
Student > Bachelor | 3 | 9% |
Student > Master | 3 | 9% |
Other | 6 | 18% |
Unknown | 6 | 18% |
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Neuroscience | 6 | 18% |
Social Sciences | 3 | 9% |
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Psychology | 2 | 6% |
Other | 4 | 12% |
Unknown | 7 | 21% |