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Epilepsy an Update on Disease Mechanisms: The Potential Role of MicroRNAs

Overview of attention for article published in Frontiers in Neurology, March 2018
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Title
Epilepsy an Update on Disease Mechanisms: The Potential Role of MicroRNAs
Published in
Frontiers in Neurology, March 2018
DOI 10.3389/fneur.2018.00176
Pubmed ID
Authors

Michele Simonato

Abstract

So far, research on epilepsy mechanisms has been designed mainly using animal models and tracking down molecular mechanisms underlying seizures in that model. While this approach is clearly valuable, it can be questioned if it is the best possible. One attractive alternative approach may stem from the consideration of epilepsy as a complex disease of a very complex organ, the brain. This short review summarizes data from analyses of the alterations in expression of microRNAs and their target messenger RNAs in a specific brain subregion, the dentate gyrus of the hippocampus, in three experimental models of lesional epilepsy. The findings are discussed within the conceptual framework of complex systems.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 70 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 70 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 8 11%
Student > Master 7 10%
Researcher 6 9%
Student > Ph. D. Student 4 6%
Professor 3 4%
Other 9 13%
Unknown 33 47%
Readers by discipline Count As %
Medicine and Dentistry 14 20%
Neuroscience 7 10%
Biochemistry, Genetics and Molecular Biology 5 7%
Agricultural and Biological Sciences 3 4%
Pharmacology, Toxicology and Pharmaceutical Science 3 4%
Other 2 3%
Unknown 36 51%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 April 2018.
All research outputs
#18,591,506
of 23,028,364 outputs
Outputs from Frontiers in Neurology
#7,863
of 11,923 outputs
Outputs of similar age
#258,139
of 332,288 outputs
Outputs of similar age from Frontiers in Neurology
#180
of 262 outputs
Altmetric has tracked 23,028,364 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,923 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.3. This one is in the 25th percentile – i.e., 25% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 332,288 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 262 others from the same source and published within six weeks on either side of this one. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.