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Therapeutic Values of Human Urinary Kallidinogenase on Cerebrovascular Diseases

Overview of attention for article published in Frontiers in Neurology, June 2018
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Title
Therapeutic Values of Human Urinary Kallidinogenase on Cerebrovascular Diseases
Published in
Frontiers in Neurology, June 2018
DOI 10.3389/fneur.2018.00403
Pubmed ID
Authors

Zhenyu Wei, Yi Lyu, XiaoLi Yang, Xin Chen, Ping Zhong, Danhong Wu

Abstract

The term "tissue kallikrein" is used to describe a group of serine proteases shared considerable sequence homology and colocalize in the same chromosomal locus 19q13. 2-q13.4. It has been widely discovered in various tissues and has been proved to be involved in kinds of pathophysiological processes, such as inhibiting oxidative stress, inflammation, apoptosis, fibrosis and promoting angiogenesis, and neurogenesis. Human Urinary Kallidinogenase (HUK) extracted from human urine is a member of tissue kallikrein which could convert kininogen to kinin and hence improve the plasma kinin level. Medical value of HUK has been widely investigated in China, especially on acute ischemic stroke. In this review, we will summarize the therapeutic values of Human Urinary Kallidinogenase on acute ischemic stroke and its potential mechanisms.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 7 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 7 100%

Demographic breakdown

Readers by professional status Count As %
Other 4 57%
Researcher 1 14%
Student > Bachelor 1 14%
Unknown 1 14%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 1 14%
Biochemistry, Genetics and Molecular Biology 1 14%
Neuroscience 1 14%
Medicine and Dentistry 1 14%
Unknown 3 43%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 June 2018.
All research outputs
#20,520,426
of 23,088,369 outputs
Outputs from Frontiers in Neurology
#9,013
of 11,997 outputs
Outputs of similar age
#289,334
of 329,782 outputs
Outputs of similar age from Frontiers in Neurology
#246
of 315 outputs
Altmetric has tracked 23,088,369 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,997 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.3. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 329,782 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 315 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.