The data shown below were collected from the profiles of 23 X users who shared this research output. Click here to find out more about how the information was compiled.
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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Cortical and Subcortical Alterations in Medication Overuse Headache
|
|---|---|
| Published in |
Frontiers in Neurology, June 2018
|
| DOI | 10.3389/fneur.2018.00499 |
| Pubmed ID | |
| Authors |
Jan Mehnert, Julia Hebestreit, Arne May |
| Abstract |
Medication-overuse headache is an increasing problem in headache clinics and therapy includes drug withdrawal. Although it has been shown that the orbitofrontal cortex is hypo-metabolic and exhibits less gray matter in these patients the functional role of this finding is still unclear as virtually no functional imaging studies exploring withdrawal of medication have been published. We compared structural and functional magnetic resonance images of 18 patients before and after drug withdrawal with age and gender matched controls using a well-established trigeminal, nociceptive fMRI paradigm. We reproduced structural changes in the orbitofrontal cortex of the patients which highly correlated with the clinical outcome of medication withdrawal. The neuronal activity before drug withdrawal in pain related regions (operculum, insula, spinal trigeminal nucleus) was reduced compared to after drug withdrawal and the orbitofrontal cortex showed a reduced functional connectivity to the nociceptive input region (spinal trigeminal nucleus) and the cerebellum which regained after withdrawal. These data suggest the seminal role of the orbitofrontal cortex as a mediator between bottom-up and top-down stream in headache processing. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 13% |
| United Kingdom | 3 | 13% |
| Germany | 3 | 13% |
| Brazil | 2 | 9% |
| Switzerland | 1 | 4% |
| Spain | 1 | 4% |
| Mexico | 1 | 4% |
| Canada | 1 | 4% |
| Unknown | 8 | 35% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 18 | 78% |
| Scientists | 3 | 13% |
| Practitioners (doctors, other healthcare professionals) | 1 | 4% |
| Science communicators (journalists, bloggers, editors) | 1 | 4% |
Mendeley readers
The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 17 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 3 | 18% |
| Researcher | 3 | 18% |
| Student > Master | 2 | 12% |
| Student > Bachelor | 1 | 6% |
| Student > Postgraduate | 1 | 6% |
| Other | 0 | 0% |
| Unknown | 7 | 41% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 6 | 35% |
| Neuroscience | 2 | 12% |
| Arts and Humanities | 1 | 6% |
| Social Sciences | 1 | 6% |
| Unknown | 7 | 41% |
Attention Score in Context
This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 October 2018.
All research outputs
#2,630,438
of 23,092,602 outputs
Outputs from Frontiers in Neurology
#1,435
of 12,007 outputs
Outputs of similar age
#55,541
of 328,981 outputs
Outputs of similar age from Frontiers in Neurology
#22
of 318 outputs
Altmetric has tracked 23,092,602 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 12,007 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.3. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 328,981 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 318 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.