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Sleep spindle alterations in patients with Parkinson's disease

Overview of attention for article published in Frontiers in Human Neuroscience, May 2015
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Title
Sleep spindle alterations in patients with Parkinson's disease
Published in
Frontiers in Human Neuroscience, May 2015
DOI 10.3389/fnhum.2015.00233
Pubmed ID
Authors

Julie A. E. Christensen, Miki Nikolic, Simon C. Warby, Henriette Koch, Marielle Zoetmulder, Rune Frandsen, Keivan K. Moghadam, Helge B. D. Sorensen, Emmanuel Mignot, Poul J. Jennum

Abstract

The aim of this study was to identify changes of sleep spindles (SS) in the EEG of patients with Parkinson's disease (PD). Five sleep experts manually identified SS at a central scalp location (C3-A2) in 15 PD and 15 age- and sex-matched control subjects. Each SS was given a confidence score, and by using a group consensus rule, 901 SS were identified and characterized by their (1) duration, (2) oscillation frequency, (3) maximum peak-to-peak amplitude, (4) percent-to-peak amplitude, and (5) density. Between-group comparisons were made for all SS characteristics computed, and significant changes for PD patients vs. control subjects were found for duration, oscillation frequency, maximum peak-to-peak amplitude and density. Specifically, SS density was lower, duration was longer, oscillation frequency slower and maximum peak-to-peak amplitude higher in patients vs. We also computed inter-expert reliability in SS scoring and found a significantly lower reliability in scoring definite SS in patients when compared to controls. How neurodegeneration in PD could influence SS characteristics is discussed. We also note that the SS morphological changes observed here may affect automatic detection of SS in patients with PD or other neurodegenerative disorders (NDDs).

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 104 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
United States 1 <1%
Denmark 1 <1%
Unknown 101 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 17%
Researcher 14 13%
Student > Master 11 11%
Student > Bachelor 10 10%
Student > Doctoral Student 7 7%
Other 17 16%
Unknown 27 26%
Readers by discipline Count As %
Neuroscience 26 25%
Engineering 9 9%
Medicine and Dentistry 8 8%
Psychology 8 8%
Agricultural and Biological Sciences 5 5%
Other 12 12%
Unknown 36 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 July 2015.
All research outputs
#13,941,015
of 22,803,211 outputs
Outputs from Frontiers in Human Neuroscience
#4,302
of 7,145 outputs
Outputs of similar age
#134,040
of 264,364 outputs
Outputs of similar age from Frontiers in Human Neuroscience
#122
of 185 outputs
Altmetric has tracked 22,803,211 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,145 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.6. This one is in the 36th percentile – i.e., 36% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 264,364 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 185 others from the same source and published within six weeks on either side of this one. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.