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Electrical Stimulation Elicits Neural Stem Cells Activation: New Perspectives in CNS Repair

Overview of attention for article published in Frontiers in Human Neuroscience, October 2015
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (57th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (55th percentile)

Mentioned by

patent
1 patent

Citations

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55 Dimensions

Readers on

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185 Mendeley
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Title
Electrical Stimulation Elicits Neural Stem Cells Activation: New Perspectives in CNS Repair
Published in
Frontiers in Human Neuroscience, October 2015
DOI 10.3389/fnhum.2015.00586
Pubmed ID
Authors

Yanhua Huang, YeE Li, Jian Chen, Hongxing Zhou, Sheng Tan

Abstract

Researchers are enthusiastically concerned about neural stem cell (NSC) therapy in a wide array of diseases, including stroke, neurodegenerative disease, spinal cord injury, and depression. Although enormous evidences have demonstrated that neurobehavioral improvement may benefit from NSC-supporting regeneration in animal models, approaches to endogenous and transplanted NSCs are blocked by hurdles of migration, proliferation, maturation, and integration of NSCs. Electrical stimulation (ES) may be a selective non-drug approach for mobilizing NSCs in the central nervous system. This technique is suitable for clinical application, because it is well established and its potential complications are manageable. Here, we provide a comprehensive review of the emerging positive role of different electrical cues in regulating NSC biology in vitro and in vivo, as well as biomaterial-based and chemical stimulation of NSCs. In the future, ES combined with stem cell therapy or other cues probably becomes an approach for promoting brain repair.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 185 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 1%
Croatia 1 <1%
Unknown 182 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 37 20%
Student > Ph. D. Student 29 16%
Researcher 24 13%
Student > Master 22 12%
Student > Doctoral Student 14 8%
Other 32 17%
Unknown 27 15%
Readers by discipline Count As %
Medicine and Dentistry 29 16%
Engineering 27 15%
Neuroscience 23 12%
Agricultural and Biological Sciences 18 10%
Biochemistry, Genetics and Molecular Biology 16 9%
Other 25 14%
Unknown 47 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 April 2019.
All research outputs
#7,468,612
of 22,832,057 outputs
Outputs from Frontiers in Human Neuroscience
#3,286
of 7,155 outputs
Outputs of similar age
#95,692
of 283,765 outputs
Outputs of similar age from Frontiers in Human Neuroscience
#69
of 159 outputs
Altmetric has tracked 22,832,057 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,155 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.6. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 283,765 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 57% of its contemporaries.
We're also able to compare this research output to 159 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.