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Comparing Aging and Fitness Effects on Brain Anatomy

Overview of attention for article published in Frontiers in Human Neuroscience, June 2016
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  • Good Attention Score compared to outputs of the same age and source (65th percentile)

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Title
Comparing Aging and Fitness Effects on Brain Anatomy
Published in
Frontiers in Human Neuroscience, June 2016
DOI 10.3389/fnhum.2016.00286
Pubmed ID
Authors

Mark A. Fletcher, Kathy A. Low, Rachel Boyd, Benjamin Zimmerman, Brian A. Gordon, Chin H. Tan, Nils Schneider-Garces, Bradley P. Sutton, Gabriele Gratton, Monica Fabiani

Abstract

Recent studies suggest that cardiorespiratory fitness (CRF) mitigates the brain's atrophy typically associated with aging, via a variety of beneficial mechanisms. One could argue that if CRF is generally counteracting the negative effects of aging, the same regions that display the greatest age-related volumetric loss should also show the largest beneficial effects of fitness. To test this hypothesis we examined structural MRI data from 54 healthy older adults (ages 55-87), to determine the overlap, across brain regions, of the profiles of age and fitness effects. Results showed that lower fitness and older age are associated with atrophy in several brain regions, replicating past studies. However, when the profiles of age and fitness effects were compared using a number of statistical approaches, the effects were not entirely overlapping. Interestingly, some of the regions that were most influenced by age were among those not influenced by fitness. Presumably, the age-related atrophy occurring in these regions is due to factors that are more impervious to the beneficial effects of fitness. Possible mechanisms supporting regional heterogeneity may include differential involvement in motor function, the presence of adult neurogenesis, and differential sensitivity to cerebrovascular, neurotrophic and metabolic factors.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Canada 1 2%
Unknown 57 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 13 22%
Student > Master 10 17%
Student > Ph. D. Student 10 17%
Student > Bachelor 5 8%
Professor 4 7%
Other 5 8%
Unknown 12 20%
Readers by discipline Count As %
Neuroscience 13 22%
Psychology 8 14%
Agricultural and Biological Sciences 5 8%
Medicine and Dentistry 5 8%
Sports and Recreations 5 8%
Other 7 12%
Unknown 16 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 May 2017.
All research outputs
#6,166,674
of 22,875,477 outputs
Outputs from Frontiers in Human Neuroscience
#2,555
of 7,167 outputs
Outputs of similar age
#101,301
of 351,562 outputs
Outputs of similar age from Frontiers in Human Neuroscience
#63
of 186 outputs
Altmetric has tracked 22,875,477 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 7,167 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.6. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 351,562 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 186 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.