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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Structural Imaging Changes and Behavioral Correlates in Patients with Crohn’s Disease in Remission
|
|---|---|
| Published in |
Frontiers in Human Neuroscience, September 2016
|
| DOI | 10.3389/fnhum.2016.00460 |
| Pubmed ID | |
| Authors |
Veena A. Nair, Poonam Beniwal-Patel, Ifeanyi Mbah, Brittany M. Young, Vivek Prabhakaran, Sumona Saha |
| Abstract |
Background: Crohn's disease (CD) is a subtype of inflammatory bowel disease caused by immune-mediated inflammation in the gastrointestinal tract. The extent of morphologic brain alterations and their associated cognitive and affective impairments remain poorly characterized. Aims: We used magnetic resonance imaging to identify structural brain differences between patients with Crohn's disease in remission compared to age-matched healthy controls and evaluated for structural-behavioral correlates. Methods: Nineteen patients and 20 healthy, age-matched controls were recruited in the study. Group differences in brain morphometric measures and correlations between brain measures and performance on a cognitive task, the verbal fluency (VF) task, were examined. Correlations between brain measures and cognitive measures as well as self-reported measures of depression, personality, and affective scales were examined. Results: Patients showed significant cortical thickening in the left superior frontal region compared to controls. Significant group differences were observed in sub-cortical volume measures in both hemispheres. Investigation of brain-behavior correlations revealed significant group differences in the correlation between cortical surface area and VF performance, although behavioral performance was equivalent between the two groups. The left middle temporal surface area was a significant predictor of VF performance with controls showing a significant positive correlation between these measures, and patients showing the opposite effect. Conclusion: Our results indicate key differences in structural brain measures in patients with CD compared to controls. Additionally, correlation between brain measures and behavioral responses suggest there may be a neural basis to the alterations in patients' cognitive and affective responses. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 68 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 68 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 10 | 15% |
| Student > Bachelor | 9 | 13% |
| Student > Master | 8 | 12% |
| Researcher | 6 | 9% |
| Other | 4 | 6% |
| Other | 14 | 21% |
| Unknown | 17 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 13 | 19% |
| Medicine and Dentistry | 13 | 19% |
| Neuroscience | 10 | 15% |
| Agricultural and Biological Sciences | 5 | 7% |
| Nursing and Health Professions | 4 | 6% |
| Other | 8 | 12% |
| Unknown | 15 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 October 2016.
All research outputs
#15,384,302
of 22,888,307 outputs
Outputs from Frontiers in Human Neuroscience
#5,276
of 7,172 outputs
Outputs of similar age
#186,958
of 294,932 outputs
Outputs of similar age from Frontiers in Human Neuroscience
#108
of 151 outputs
Altmetric has tracked 22,888,307 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,172 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.6. This one is in the 20th percentile – i.e., 20% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 294,932 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 151 others from the same source and published within six weeks on either side of this one. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.