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Transcranial Direct Current Stimulation over the Dorsolateral Prefrontal Cortex in Schizophrenia: A Quantitative Review of Cognitive Outcomes

Overview of attention for article published in Frontiers in Human Neuroscience, February 2017
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Title
Transcranial Direct Current Stimulation over the Dorsolateral Prefrontal Cortex in Schizophrenia: A Quantitative Review of Cognitive Outcomes
Published in
Frontiers in Human Neuroscience, February 2017
DOI 10.3389/fnhum.2017.00044
Pubmed ID
Authors

Joshua E. Mervis, Riley J. Capizzi, Elias Boroda, Angus W. MacDonald

Abstract

Cognitive deficits are a core and disabling feature of psychotic disorders, specifically schizophrenia. Current treatments for impaired cognition in schizophrenia remain insufficient. Recent research suggests transcranial direct current stimulation (tDCS) targeting the dorsolateral prefrontal cortex can potentiate cognitive improvements in healthy individuals and those with psychiatric conditions, such as schizophrenia. However, this burgeoning literature has not been quantitatively evaluated. Through a literature search and quantitative review, we identified 194 papers on tDCS, psychosis, and cognition. Selection criteria included pre/post design and sham control to achieve specific sham-adjusted effect sizes. The 6 retained studies all address schizophrenia populations and include single and repeated stimulation, as well as within and between subject designs. Small positive effects were found for anodal stimulation on behavioral measures of attention and working memory, with tentative findings for cognitive ability and memory. Cathodal stimulation yielded a small positive effect on behaviorally measured cognitive ability. Neurophysiological measures of attention showed a small to medium down-modulation effect for anodal stimulation. Implications of these findings and guidelines for future research are discussed. As revealed by this report, due to the paucity of data available, much remains unknown regarding the clinical efficacy of tDCS in schizophrenia.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 166 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
Unknown 165 99%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 54 33%
Researcher 22 13%
Student > Master 18 11%
Student > Ph. D. Student 14 8%
Student > Doctoral Student 11 7%
Other 22 13%
Unknown 25 15%
Readers by discipline Count As %
Medicine and Dentistry 44 27%
Psychology 32 19%
Nursing and Health Professions 22 13%
Neuroscience 21 13%
Computer Science 3 2%
Other 10 6%
Unknown 34 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 February 2017.
All research outputs
#15,431,277
of 22,940,083 outputs
Outputs from Frontiers in Human Neuroscience
#5,280
of 7,178 outputs
Outputs of similar age
#256,631
of 420,200 outputs
Outputs of similar age from Frontiers in Human Neuroscience
#142
of 182 outputs
Altmetric has tracked 22,940,083 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,178 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.6. This one is in the 20th percentile – i.e., 20% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 420,200 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 30th percentile – i.e., 30% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 182 others from the same source and published within six weeks on either side of this one. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.