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Effective Connectivity in Response to Posture Changes in Elderly Subjects as Assessed Using Functional Near-Infrared Spectroscopy

Overview of attention for article published in Frontiers in Human Neuroscience, March 2018
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Title
Effective Connectivity in Response to Posture Changes in Elderly Subjects as Assessed Using Functional Near-Infrared Spectroscopy
Published in
Frontiers in Human Neuroscience, March 2018
DOI 10.3389/fnhum.2018.00098
Pubmed ID
Authors

Congcong Huo, Ming Zhang, Lingguo Bu, Gongcheng Xu, Ying Liu, Zengyong Li, Lingling Sun

Abstract

This study aims to assess the posture-related changes in frequency-specific effective connectivity (EC) in elderly subjects by coupling function measured using functional near-infrared spectroscopy (fNIRS). The fNIRS signals were continuously recorded from the bilateral prefrontal cortex (PFC), motor cortex (MC), and occipital lobe (OL) in 17 healthy elderly and 19 healthy young subjects during sitting and standing states. EC was calculated based on Dynamic Bayesian inference in one low frequency interval I: 0.052-0.145 Hz and one very low frequency interval II: 0.021-0.052 Hz. Results show that in response to posture change, the coupling strength significantly increased in interval I of the young group from right PFC to MC (p < 0.05). Meanwhile, the coupling strength of the elderly group was significantly increased in interval II from the left PFC to right PFC (p = 0.008) and to left MC (p = 0.031) in the standing state as compared with that in the sitting state. Compared with that of the young group, the coupling strength of the elderly group was significantly decreased (p < 0.05) between the right PFC and left PFC in interval I and from PFC and OL to MC in interval II during the sitting state. The decreased EC in interval I was also positively correlated with cognitive scores in the elderly group. In addition, the coupling strength from MC to PFC in interval II during standing state was significantly increased in elderly subjects as compared with that in the young group. These results revealed the age-related changes in reorganization of interregional interactions for different postures. These findings may provide evidence of impaired cognitive function in the elderly and can deepen the understanding on age-related changes in neurovascular coupling.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 60 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 10 17%
Student > Ph. D. Student 7 12%
Unspecified 6 10%
Student > Master 5 8%
Student > Doctoral Student 3 5%
Other 10 17%
Unknown 19 32%
Readers by discipline Count As %
Unspecified 6 10%
Neuroscience 5 8%
Nursing and Health Professions 5 8%
Psychology 4 7%
Engineering 4 7%
Other 15 25%
Unknown 21 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 March 2018.
All research outputs
#14,839,807
of 23,025,074 outputs
Outputs from Frontiers in Human Neuroscience
#4,858
of 7,194 outputs
Outputs of similar age
#199,292
of 333,151 outputs
Outputs of similar age from Frontiers in Human Neuroscience
#115
of 147 outputs
Altmetric has tracked 23,025,074 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,194 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.6. This one is in the 31st percentile – i.e., 31% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 333,151 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 147 others from the same source and published within six weeks on either side of this one. This one is in the 20th percentile – i.e., 20% of its contemporaries scored the same or lower than it.