Neglect-Like Effects on Drawing Symmetry Induced by Adaptation to a Laterally Asymmetric Visuomotor Delay

Chen Avraham, Guy Avraham, Ferdinando A. Mussa-Ivaldi, Ilana Nisky

In daily interactions, our sensorimotor system accounts for spatial and temporal discrepancies between the senses. Functional lateralization between hemispheres causes differences in attention and in the control of action across the left and right workspaces. In addition, differences in transmission delays between modalities affect movement control and internal representations. Studies on motor impairments such as hemispatial neglect syndrome suggested a link between lateral spatial biases and temporal processing. To understand this link, we computationally modeled and experimentally validated the effect of laterally asymmetric delay in visual feedback on motor learning and its transfer to the control of drawing movements without visual feedback. In the behavioral experiments, we asked healthy participants to perform lateral reaching movements while adapting to delayed visual feedback in either left, right, or both workspaces. We found that the adaptation transferred to blind drawing and caused movement elongation, which is consistent with a state representation of the delay. However, the pattern of the spatial effect varied between conditions: whereas adaptation to delay in only the left workspace or in the whole workspace caused selective leftward elongation, adaptation to delay in only the right workspace caused drawing elongation in both directions. We simulated arm movements according to different models of perceptual and motor spatial asymmetry in the representation of delay and found that the best model that accounts for our results combines both perceptual and motor asymmetry between the hemispheres. These results provide direct evidence for an asymmetrical processing of delayed visual feedback that is associated with both perceptual and motor biases that are similar to those observed in hemispatial neglect syndrome.