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The role of leptin in the control of insulin-glucose axis

Overview of attention for article published in Frontiers in Neuroscience, January 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (85th percentile)
  • Good Attention Score compared to outputs of the same age and source (71st percentile)

Mentioned by

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8 X users
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4 Facebook pages
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5 Wikipedia pages
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2 YouTube creators

Citations

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178 Dimensions

Readers on

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382 Mendeley
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Title
The role of leptin in the control of insulin-glucose axis
Published in
Frontiers in Neuroscience, January 2013
DOI 10.3389/fnins.2013.00051
Pubmed ID
Authors

Marie Amitani, Akihiro Asakawa, Haruka Amitani, Akio Inui

Abstract

Obesity and diabetes mellitus are great public health concerns throughout the world because of their increasing incidence and prevalence. Leptin, the adipocyte hormone, is well known for its role in the regulation of food intake and energy expenditure. In addition to the regulation of appetite and satiety that recently has attracted much attentions, insight has also been gained into the critical role of leptin in the control of the insulin-glucose axis, peripheral glucose and insulin responsiveness. Since the discovery of leptin, leptin has been taken for its therapeutic potential to obesity and diabetes. Recently, the therapeutic effects of central leptin gene therapy have been reported in insulin-deficient diabetes in obesity animal models such as ob/ob mise, diet-induced obese mice, and insulin-deficient type 1 diabetes mice, and also in patients with inactivating mutations in the leptin gene. Herein, we review the role of leptin in regulating feeding behavior and glucose metabolism and also the therapeutic potential of leptin in obesity and diabetes mellitus.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 382 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 1 <1%
Germany 1 <1%
Italy 1 <1%
Brazil 1 <1%
Spain 1 <1%
Japan 1 <1%
United States 1 <1%
Unknown 375 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 58 15%
Student > Bachelor 53 14%
Student > Master 42 11%
Researcher 41 11%
Student > Doctoral Student 17 4%
Other 59 15%
Unknown 112 29%
Readers by discipline Count As %
Agricultural and Biological Sciences 63 16%
Medicine and Dentistry 60 16%
Biochemistry, Genetics and Molecular Biology 54 14%
Pharmacology, Toxicology and Pharmaceutical Science 15 4%
Neuroscience 15 4%
Other 54 14%
Unknown 121 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 June 2024.
All research outputs
#4,291,253
of 26,132,653 outputs
Outputs from Frontiers in Neuroscience
#3,480
of 11,761 outputs
Outputs of similar age
#41,198
of 293,285 outputs
Outputs of similar age from Frontiers in Neuroscience
#69
of 246 outputs
Altmetric has tracked 26,132,653 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 11,761 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.1. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 293,285 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 246 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.