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Role of membrane biophysics in Alzheimer's–related cell pathways

Overview of attention for article published in Frontiers in Neuroscience, May 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (84th percentile)
  • Good Attention Score compared to outputs of the same age and source (76th percentile)

Mentioned by

news
1 news outlet
twitter
2 X users

Citations

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28 Dimensions

Readers on

mendeley
87 Mendeley
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Title
Role of membrane biophysics in Alzheimer's–related cell pathways
Published in
Frontiers in Neuroscience, May 2015
DOI 10.3389/fnins.2015.00186
Pubmed ID
Authors

Donghui Zhu, Brittani L. Bungart, Xiaoguang Yang, Zhaxybay Zhumadilov, James C-M. Lee, Sholpan Askarova

Abstract

Cellular membrane alterations are commonly observed in many diseases, including Alzheimer's disease (AD). Membrane biophysical properties, such as membrane molecular order, membrane fluidity, organization of lipid rafts, and adhesion between membrane and cytoskeleton, play an important role in various cellular activities and functions. While membrane biophysics impacts a broad range of cellular pathways, this review addresses the role of membrane biophysics in amyloid-β peptide aggregation, Aβ-induced oxidative pathways, amyloid precursor protein processing, and cerebral endothelial functions in AD. Understanding the mechanism(s) underlying the effects of cell membrane properties on cellular processes should shed light on the development of new preventive and therapeutic strategies for this devastating disease.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 87 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Denmark 1 1%
Belgium 1 1%
Unknown 84 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 17 20%
Student > Ph. D. Student 16 18%
Student > Postgraduate 7 8%
Student > Doctoral Student 6 7%
Student > Master 6 7%
Other 15 17%
Unknown 20 23%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 14 16%
Agricultural and Biological Sciences 14 16%
Chemistry 9 10%
Neuroscience 7 8%
Medicine and Dentistry 7 8%
Other 13 15%
Unknown 23 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 June 2015.
All research outputs
#3,560,742
of 25,371,288 outputs
Outputs from Frontiers in Neuroscience
#2,873
of 11,537 outputs
Outputs of similar age
#44,093
of 280,149 outputs
Outputs of similar age from Frontiers in Neuroscience
#26
of 114 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 11,537 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.9. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,149 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 114 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 76% of its contemporaries.