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TRICK or TRP? What Trpc2−/− mice tell us about vomeronasal organ mediated innate behaviors

Overview of attention for article published in Frontiers in Neuroscience, June 2015
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Title
TRICK or TRP? What Trpc2−/− mice tell us about vomeronasal organ mediated innate behaviors
Published in
Frontiers in Neuroscience, June 2015
DOI 10.3389/fnins.2015.00221
Pubmed ID
Authors

C. Ron Yu

Abstract

The vomeronasal organ (VNO) plays an important role in mediating semiochemical communications and social behaviors in terrestrial species. Genetic knockout of individual components in the signaling pathways has been used to probe vomeronasal functions, and has provided much insights into how the VNO orchestrates innate behaviors. However, all data do not agree. In particular, knocking out Trpc2, a member of the TRP family of non-selective cationic channel thought to be the main transduction channel in the VNO, results in a number of fascinating behavioral phenotypes that have not been observed in other animals whose vomeronasal function is disrupted. Recent studies have identified signaling pathways that operate in parallel of Trpc2, raising the possibility that Trpc2 mutant animals may display neomorphic behaviors. In this article, I provide a critical analysis of emerging evidence to reconcile the discrepancies and discuss their implications.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 2 6%
Unknown 34 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 28%
Student > Bachelor 6 17%
Student > Doctoral Student 4 11%
Student > Postgraduate 3 8%
Other 2 6%
Other 8 22%
Unknown 3 8%
Readers by discipline Count As %
Agricultural and Biological Sciences 16 44%
Neuroscience 10 28%
Biochemistry, Genetics and Molecular Biology 2 6%
Medicine and Dentistry 2 6%
Psychology 1 3%
Other 0 0%
Unknown 5 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 July 2015.
All research outputs
#15,983,785
of 25,374,917 outputs
Outputs from Frontiers in Neuroscience
#6,983
of 11,541 outputs
Outputs of similar age
#145,603
of 278,312 outputs
Outputs of similar age from Frontiers in Neuroscience
#72
of 108 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 36th percentile – i.e., 36% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,541 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.9. This one is in the 38th percentile – i.e., 38% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 278,312 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 108 others from the same source and published within six weeks on either side of this one. This one is in the 30th percentile – i.e., 30% of its contemporaries scored the same or lower than it.