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Noninvasive Focused Ultrasound Stimulation Can Modulate Phase-Amplitude Coupling between Neuronal Oscillations in the Rat Hippocampus

Overview of attention for article published in Frontiers in Neuroscience, July 2016
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  • Above-average Attention Score compared to outputs of the same age and source (59th percentile)

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Title
Noninvasive Focused Ultrasound Stimulation Can Modulate Phase-Amplitude Coupling between Neuronal Oscillations in the Rat Hippocampus
Published in
Frontiers in Neuroscience, July 2016
DOI 10.3389/fnins.2016.00348
Pubmed ID
Authors

Yi Yuan, Jiaqing Yan, Zhitao Ma, Xiaoli Li

Abstract

Noninvasive focused ultrasound stimulation (FUS) can be used to modulate neural activity with high spatial resolution. Phase-amplitude coupling (PAC) between neuronal oscillations is tightly associated with cognitive processes, including learning, attention, and memory. In this study, we investigated the effect of FUS on PAC between neuronal oscillations and established the relationship between the PAC index and ultrasonic intensity. The rat hippocampus was stimulated using focused ultrasound at different spatial-average pulse-average ultrasonic intensities (3.9, 9.6, and 19.2 W/cm(2)). The local field potentials (LFPs) in the rat hippocampus were recorded before and after FUS. Then, we analyzed PAC between neuronal oscillations using a PAC calculation algorithm. Our results showed that FUS significantly modulated PAC between the theta (4-8 Hz) and gamma (30-80 Hz) bands and between the alpha (9-13 Hz) and ripple (81-200 Hz) bands in the rat hippocampus, and PAC increased with incremental increases in ultrasonic intensity.

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X Demographics

The data shown below were collected from the profiles of 9 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 66 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Unknown 65 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 23%
Researcher 9 14%
Professor 7 11%
Student > Bachelor 6 9%
Student > Master 5 8%
Other 9 14%
Unknown 15 23%
Readers by discipline Count As %
Engineering 17 26%
Neuroscience 15 23%
Medicine and Dentistry 5 8%
Physics and Astronomy 3 5%
Agricultural and Biological Sciences 3 5%
Other 6 9%
Unknown 17 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 May 2018.
All research outputs
#7,080,812
of 25,807,758 outputs
Outputs from Frontiers in Neuroscience
#4,562
of 11,715 outputs
Outputs of similar age
#111,194
of 380,103 outputs
Outputs of similar age from Frontiers in Neuroscience
#60
of 154 outputs
Altmetric has tracked 25,807,758 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 11,715 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.0. This one has gotten more attention than average, scoring higher than 60% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 380,103 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 154 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 59% of its contemporaries.