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Role of BDNF Signaling in Memory Enhancement Induced by Transcranial Direct Current Stimulation

Overview of attention for article published in Frontiers in Neuroscience, June 2018
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Title
Role of BDNF Signaling in Memory Enhancement Induced by Transcranial Direct Current Stimulation
Published in
Frontiers in Neuroscience, June 2018
DOI 10.3389/fnins.2018.00427
Pubmed ID
Authors

Sara Cocco, Maria V. Podda, Claudio Grassi

Abstract

In the recent years numerous studies have provided encouraging results supporting the use of transcranial direct current stimulation (tDCS) as non-invasive brain stimulation technique to improve motor and cognitive functions in patients suffering from neurological and neuropsychiatric disorders as well as in healthy subjects. Among the multiple effects elicited by tDCS on cognitive functions, experimental evidence and clinical findings have highlighted the beneficial impact on long-term memory. Memory deficits occur during physiological aging as well as in neurological and neurodegenerative disorders, including Alzheimer's disease (AD). In this scenario, non-invasive techniques for memory enhancement, such as tDCS, are receiving increasing attention. The knowledge of molecular mechanisms subtending tDCS effects is of pivotal importance for a more rationale use of this technique in clinical settings. Although we are still far from having a clear picture, recent literature on human and animal studies has pointed to the involvement of synaptic plasticity mechanisms in mediating tDCS effects on long-term memory. Here we review these studies focusing on the neurotrophin "brain-derived neurotrophic factor" (BDNF) as critical tDCS effector.

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The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 111 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 111 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 15 14%
Student > Bachelor 15 14%
Student > Ph. D. Student 12 11%
Student > Master 10 9%
Other 7 6%
Other 20 18%
Unknown 32 29%
Readers by discipline Count As %
Neuroscience 31 28%
Psychology 13 12%
Medicine and Dentistry 5 5%
Pharmacology, Toxicology and Pharmaceutical Science 4 4%
Unspecified 4 4%
Other 15 14%
Unknown 39 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 July 2018.
All research outputs
#16,728,456
of 25,385,509 outputs
Outputs from Frontiers in Neuroscience
#7,428
of 11,542 outputs
Outputs of similar age
#211,102
of 342,601 outputs
Outputs of similar age from Frontiers in Neuroscience
#174
of 233 outputs
Altmetric has tracked 25,385,509 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,542 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.0. This one is in the 31st percentile – i.e., 31% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 342,601 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 233 others from the same source and published within six weeks on either side of this one. This one is in the 20th percentile – i.e., 20% of its contemporaries scored the same or lower than it.