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Reliability of Static and Dynamic Network Metrics in the Resting-State: A MEG-Beamformed Connectivity Analysis

Overview of attention for article published in Frontiers in Neuroscience, August 2018
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Title
Reliability of Static and Dynamic Network Metrics in the Resting-State: A MEG-Beamformed Connectivity Analysis
Published in
Frontiers in Neuroscience, August 2018
DOI 10.3389/fnins.2018.00506
Pubmed ID
Authors

Stavros I. Dimitriadis, Bethany Routley, David E. Linden, Krish D. Singh

Abstract

The resting activity of the brain can be described by so-called intrinsic connectivity networks (ICNs), which consist of spatially and temporally distributed, but functionally connected, nodes. The coordinated activity of the resting state can be explored via magnetoencephalography (MEG) by studying frequency-dependent functional brain networks at the source level. Although many algorithms for the analysis of brain connectivity have been proposed, the reliability of network metrics derived from both static and dynamic functional connectivity is still unknown. This is a particular problem for studies of associations between ICN metrics and personality variables or other traits, and for studies of differences between patient and control groups, which both depend critically on the reliability of the metrics used. A detailed investigation of the reliability of metrics derived from resting-state MEG repeat scans is therefore a prerequisite for the development of connectomic biomarkers. Here, we first estimated both static (SFC) and dynamic functional connectivity (DFC) after beamforming source reconstruction using the imaginary part of the phase locking index (iPLV) and the correlation of the amplitude envelope (CorEnv). Using our approach, functional network microstates (FCμstates) were derived from the DFC and chronnectomics were computed from the evolution of FCμstates across experimental time. In both temporal scales, the reliability of network metrics (SFC), the FCμstates and the related chronnectomics were evaluated for every frequency band. Chronnectomic statistics and FCμstates were generally more reliable than node-wise static network metrics. CorEnv-based network metrics were more reproducible at the static approach. The reliability of chronnectomics have been evaluated also in a second dataset. This study encourages the analysis of MEG resting-state via DFC.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 77 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 77 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 17 22%
Researcher 12 16%
Student > Master 7 9%
Student > Bachelor 6 8%
Student > Doctoral Student 5 6%
Other 9 12%
Unknown 21 27%
Readers by discipline Count As %
Neuroscience 14 18%
Engineering 7 9%
Computer Science 4 5%
Psychology 4 5%
Medicine and Dentistry 4 5%
Other 13 17%
Unknown 31 40%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 August 2018.
All research outputs
#8,266,724
of 25,385,509 outputs
Outputs from Frontiers in Neuroscience
#5,239
of 11,542 outputs
Outputs of similar age
#131,484
of 341,622 outputs
Outputs of similar age from Frontiers in Neuroscience
#122
of 231 outputs
Altmetric has tracked 25,385,509 research outputs across all sources so far. This one has received more attention than most of these and is in the 66th percentile.
So far Altmetric has tracked 11,542 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.0. This one has gotten more attention than average, scoring higher than 53% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 341,622 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.
We're also able to compare this research output to 231 others from the same source and published within six weeks on either side of this one. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.