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Decreased CX3CL1 Levels in the Cerebrospinal Fluid of Patients With Alzheimer’s Disease

Overview of attention for article published in Frontiers in Neuroscience, September 2018
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)
  • Good Attention Score compared to outputs of the same age and source (71st percentile)

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1 news outlet
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6 X users

Citations

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46 Dimensions

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47 Mendeley
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Title
Decreased CX3CL1 Levels in the Cerebrospinal Fluid of Patients With Alzheimer’s Disease
Published in
Frontiers in Neuroscience, September 2018
DOI 10.3389/fnins.2018.00609
Pubmed ID
Authors

Juan R. Perea, Alberto Lleó, Daniel Alcolea, Juan Fortea, Jesús Ávila, Marta Bolós

Abstract

Alzheimer's disease (AD) is a neurodegenerative disease characterized by the presence of neurofibrillary tangles, constituted by tau protein, and plaques formed by amyloid-beta protein. The disease courses with high neural damage, which leads to memory loss and death. Here we analyzed the presence of CX3CL1, a chemokine expressed by neurons, in cerebrospinal fluid (CSF) samples from control subjects and patients with mild cognitive impairment and AD dementia. CX3CL1 was decreased in the CSF of AD dementia patients compared to control subjects. However, there was not difference in plasma samples from the same subjects.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 47 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 21%
Student > Ph. D. Student 7 15%
Student > Master 4 9%
Student > Doctoral Student 3 6%
Student > Bachelor 2 4%
Other 7 15%
Unknown 14 30%
Readers by discipline Count As %
Neuroscience 19 40%
Pharmacology, Toxicology and Pharmaceutical Science 3 6%
Medicine and Dentistry 2 4%
Environmental Science 1 2%
Nursing and Health Professions 1 2%
Other 3 6%
Unknown 18 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 October 2018.
All research outputs
#3,140,239
of 25,385,509 outputs
Outputs from Frontiers in Neuroscience
#2,206
of 11,542 outputs
Outputs of similar age
#60,894
of 346,007 outputs
Outputs of similar age from Frontiers in Neuroscience
#69
of 242 outputs
Altmetric has tracked 25,385,509 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 11,542 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.0. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 346,007 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 242 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.