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Parkinson’s Disease Progression: Implicit Acquisition, Cognitive and Motor Impairments, and Medication Effects

Overview of attention for article published in Frontiers in Integrative Neuroscience, January 2012
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Title
Parkinson’s Disease Progression: Implicit Acquisition, Cognitive and Motor Impairments, and Medication Effects
Published in
Frontiers in Integrative Neuroscience, January 2012
DOI 10.3389/fnint.2012.00056
Pubmed ID
Authors

Rodrigo Pavão, André Frazão Helene, Gilberto Fernando Xavier

Abstract

Parkinson's disease (PD) symptoms have been collectively ascribed to malfunctioning of dopamine-related nigro-striatal and cortico-striatal loops. However, some doubts about this proposition are raised by controversies about the temporal progression of the impairments, and whether they are concomitant or not. The present study consists of a systematic revision of literature data on both functional PD impairments and dopaminergic medication effects in order to draw a coherent picture about the disease progression. It was done in terms of an explanatory model for the disruption of implicit knowledge acquisition, motor and cognitive impairments, and the effects of dopaminergic medication on these functions. Cognitive impairments arise at early stages of PD and stabilizes while disruption of implicit knowledge acquisition and motor impairments, are still in progression; additionally, dopaminergic medication reduces motor impairments and increases disruption of implicit knowledge acquisition. Since this model revealed consistency and plausibility when confronted with data of others studies not included in model's formulation, it may turn out to be a useful tool for understanding the multifaceted characteristics of PD.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 4%
Canada 1 4%
Brazil 1 4%
Unknown 24 89%

Demographic breakdown

Readers by professional status Count As %
Student > Doctoral Student 5 19%
Student > Master 5 19%
Student > Bachelor 4 15%
Student > Ph. D. Student 3 11%
Researcher 3 11%
Other 3 11%
Unknown 4 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 6 22%
Neuroscience 5 19%
Psychology 5 19%
Medicine and Dentistry 4 15%
Nursing and Health Professions 1 4%
Other 3 11%
Unknown 3 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 August 2012.
All research outputs
#20,165,369
of 22,675,759 outputs
Outputs from Frontiers in Integrative Neuroscience
#754
of 853 outputs
Outputs of similar age
#221,176
of 244,088 outputs
Outputs of similar age from Frontiers in Integrative Neuroscience
#74
of 93 outputs
Altmetric has tracked 22,675,759 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 853 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.3. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 93 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.