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A pivotal role of GSK-3 in synaptic plasticity

Overview of attention for article published in Frontiers in Molecular Neuroscience, January 2012
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • High Attention Score compared to outputs of the same age and source (85th percentile)

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1 news outlet
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2 X users

Citations

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155 Dimensions

Readers on

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208 Mendeley
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1 CiteULike
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Title
A pivotal role of GSK-3 in synaptic plasticity
Published in
Frontiers in Molecular Neuroscience, January 2012
DOI 10.3389/fnmol.2012.00013
Pubmed ID
Authors

Clarrisa A. Bradley, Stéphane Peineau, Changiz Taghibiglou, Celine S. Nicolas, Daniel J. Whitcomb, Zuner A. Bortolotto, Bong-Kiun Kaang, Kwangwook Cho, Yu Tian Wang, Graham L. Collingridge

Abstract

Glycogen synthase kinase-3 (GSK-3) has many cellular functions. Recent evidence suggests that it plays a key role in certain types of synaptic plasticity, in particular a form of long-term depression (LTD) that is induced by the synaptic activation of N-methyl-D-aspartate receptors (NMDARs). In the present article we summarize what is currently known concerning the roles of GSK-3 in synaptic plasticity at both glutamatergic and GABAergic synapses. We summarize its role in cognition and speculate on how alterations in the synaptic functioning of GSK-3 may be a major factor in certain neurodegenerative disorders.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 208 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 <1%
United Kingdom 2 <1%
France 1 <1%
Norway 1 <1%
Denmark 1 <1%
Mexico 1 <1%
Unknown 200 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 44 21%
Researcher 33 16%
Student > Master 29 14%
Student > Bachelor 19 9%
Professor > Associate Professor 12 6%
Other 30 14%
Unknown 41 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 51 25%
Neuroscience 48 23%
Medicine and Dentistry 20 10%
Biochemistry, Genetics and Molecular Biology 18 9%
Pharmacology, Toxicology and Pharmaceutical Science 6 3%
Other 19 9%
Unknown 46 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 November 2019.
All research outputs
#2,798,571
of 22,664,644 outputs
Outputs from Frontiers in Molecular Neuroscience
#366
of 2,822 outputs
Outputs of similar age
#22,966
of 244,053 outputs
Outputs of similar age from Frontiers in Molecular Neuroscience
#7
of 48 outputs
Altmetric has tracked 22,664,644 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,822 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 244,053 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 48 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.