↓ Skip to main content

Neuronal nicotinic acetylcholine receptors: neuroplastic changes underlying alcohol and nicotine addictions

Overview of attention for article published in Frontiers in Molecular Neuroscience, January 2012
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

news
2 news outlets
twitter
14 X users
facebook
1 Facebook page

Citations

dimensions_citation
109 Dimensions

Readers on

mendeley
208 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Neuronal nicotinic acetylcholine receptors: neuroplastic changes underlying alcohol and nicotine addictions
Published in
Frontiers in Molecular Neuroscience, January 2012
DOI 10.3389/fnmol.2012.00083
Pubmed ID
Authors

Allison A. Feduccia, Susmita Chatterjee, Selena E. Bartlett

Abstract

Addictive drugs can activate systems involved in normal reward-related learning, creating long-lasting memories of the drug's reinforcing effects and the environmental cues surrounding the experience. These memories significantly contribute to the maintenance of compulsive drug use as well as cue-induced relapse which can occur even after long periods of abstinence. Synaptic plasticity is thought to be a prominent molecular mechanism underlying drug-induced learning and memories. Ethanol and nicotine are both widely abused drugs that share a common molecular target in the brain, the neuronal nicotinic acetylcholine receptors (nAChRs). The nAChRs are ligand-gated ion channels that are vastly distributed throughout the brain and play a key role in synaptic neurotransmission. In this review, we will delineate the role of nAChRs in the development of ethanol and nicotine addiction. We will characterize both ethanol and nicotine's effects on nAChR-mediated synaptic transmission and plasticity in several key brain areas that are important for addiction. Finally, we will discuss some of the behavioral outcomes of drug-induced synaptic plasticity in animal models. An understanding of the molecular and cellular changes that occur following administration of ethanol and nicotine will lead to better therapeutic strategies.

X Demographics

X Demographics

The data shown below were collected from the profiles of 14 X users who shared this research output. Click here to find out more about how the information was compiled.
As of 1 July 2024, you may notice a temporary increase in the numbers of X profiles with Unknown location. Click here to learn more.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 208 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 <1%
France 1 <1%
Brazil 1 <1%
United Kingdom 1 <1%
Canada 1 <1%
United States 1 <1%
Unknown 202 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 43 21%
Researcher 36 17%
Student > Master 25 12%
Student > Bachelor 24 12%
Student > Doctoral Student 12 6%
Other 34 16%
Unknown 34 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 43 21%
Neuroscience 42 20%
Medicine and Dentistry 26 13%
Psychology 16 8%
Biochemistry, Genetics and Molecular Biology 14 7%
Other 27 13%
Unknown 40 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 31. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 June 2022.
All research outputs
#1,354,194
of 26,512,081 outputs
Outputs from Frontiers in Molecular Neuroscience
#94
of 3,443 outputs
Outputs of similar age
#8,293
of 254,715 outputs
Outputs of similar age from Frontiers in Molecular Neuroscience
#4
of 51 outputs
Altmetric has tracked 26,512,081 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,443 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 254,715 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 51 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.