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X Demographics
Mendeley readers
Attention Score in Context
| Title |
A network of RNA and protein interactions in Fronto Temporal Dementia
|
|---|---|
| Published in |
Frontiers in Molecular Neuroscience, March 2015
|
| DOI | 10.3389/fnmol.2015.00009 |
| Pubmed ID | |
| Authors |
Francesca Fontana, Kavitha Siva, Michela A. Denti |
| Abstract |
Frontotemporal dementia (FTD) is a neurodegenerative disorder characterized by degeneration of the fronto temporal lobes and abnormal protein inclusions. It exhibits a broad clinicopathological spectrum and has been linked to mutations in seven different genes. We will provide a picture, which connects the products of these genes, albeit diverse in nature and function, in a network. Despite the paucity of information available for some of these genes, we believe that RNA processing and post-transcriptional regulation of gene expression might constitute a common theme in the network. Recent studies have unraveled the role of mutations affecting the functions of RNA binding proteins and regulation of microRNAs. This review will combine all the recent findings on genes involved in the pathogenesis of FTD, highlighting the importance of a common network of interactions in order to study and decipher the heterogeneous clinical manifestations associated with FTD. This approach could be helpful for the research of potential therapeutic strategies. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 14% |
| Unknown | 6 | 86% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 86% |
| Scientists | 1 | 14% |
Mendeley readers
The data shown below were compiled from readership statistics for 110 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Italy | 2 | 2% |
| Germany | 1 | <1% |
| Brazil | 1 | <1% |
| Canada | 1 | <1% |
| Philippines | 1 | <1% |
| Unknown | 104 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 27 | 25% |
| Student > Ph. D. Student | 26 | 24% |
| Student > Master | 13 | 12% |
| Student > Doctoral Student | 8 | 7% |
| Student > Postgraduate | 8 | 7% |
| Other | 18 | 16% |
| Unknown | 10 | 9% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 38 | 35% |
| Biochemistry, Genetics and Molecular Biology | 22 | 20% |
| Neuroscience | 19 | 17% |
| Medicine and Dentistry | 10 | 9% |
| Psychology | 3 | 3% |
| Other | 5 | 5% |
| Unknown | 13 | 12% |
Attention Score in Context
This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 May 2015.
All research outputs
#2,717,066
of 26,374,136 outputs
Outputs from Frontiers in Molecular Neuroscience
#274
of 3,418 outputs
Outputs of similar age
#32,869
of 279,465 outputs
Outputs of similar age from Frontiers in Molecular Neuroscience
#1
of 9 outputs
Altmetric has tracked 26,374,136 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,418 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.5. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 279,465 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them