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Hemifusion in Synaptic Vesicle Cycle

Overview of attention for article published in Frontiers in Molecular Neuroscience, March 2017
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Title
Hemifusion in Synaptic Vesicle Cycle
Published in
Frontiers in Molecular Neuroscience, March 2017
DOI 10.3389/fnmol.2017.00065
Pubmed ID
Authors

Dae-Hyuk Kweon, Byoungjae Kong, Yeon-Kyun Shin

Abstract

In the neuron, early neurotransmitters are released through the fusion pore prior to the complete vesicle fusion. It has been thought that the fusion pore is a gap junction-like structure made of transmembrane domains (TMDs) of soluble N-ethylmaleimide-sensitive-factor attachment protein receptor (SNARE) proteins. However, evidence has accumulated that lipid mixing occurs prior to the neurotransmitter release through the fusion pore lined predominantly with lipids. To explain these observations, the hemifusion, a membrane structure in which two bilayers are partially merged, has emerged as a key step preceding the formation of the fusion pore. Furthermore, the hemifusion appears to be the bona fide intermediate step not only for the synaptic vesicle cycle, but for a wide range of membrane remodeling processes, such as viral membrane fusion and endocytotic membrane fission.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 34 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 24%
Student > Bachelor 8 24%
Professor > Associate Professor 2 6%
Other 2 6%
Student > Doctoral Student 2 6%
Other 7 21%
Unknown 5 15%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 13 38%
Neuroscience 6 18%
Agricultural and Biological Sciences 5 15%
Medicine and Dentistry 2 6%
Unspecified 1 3%
Other 1 3%
Unknown 6 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 April 2017.
All research outputs
#18,539,663
of 22,961,203 outputs
Outputs from Frontiers in Molecular Neuroscience
#2,281
of 2,900 outputs
Outputs of similar age
#235,310
of 308,429 outputs
Outputs of similar age from Frontiers in Molecular Neuroscience
#88
of 105 outputs
Altmetric has tracked 22,961,203 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,900 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 14th percentile – i.e., 14% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 308,429 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 105 others from the same source and published within six weeks on either side of this one. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.