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Cholinergic modulation of hippocampal network function

Overview of attention for article published in Frontiers in Synaptic Neuroscience, January 2013
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2 X users
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1 Redditor

Citations

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340 Mendeley
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Title
Cholinergic modulation of hippocampal network function
Published in
Frontiers in Synaptic Neuroscience, January 2013
DOI 10.3389/fnsyn.2013.00002
Pubmed ID
Authors

Leonor M. Teles-Grilo Ruivo, Jack R. Mellor

Abstract

Cholinergic septohippocampal projections from the medial septal area to the hippocampus are proposed to have important roles in cognition by modulating properties of the hippocampal network. However, the precise spatial and temporal profile of acetylcholine release in the hippocampus remains unclear making it difficult to define specific roles for cholinergic transmission in hippocampal dependent behaviors. This is partly due to a lack of tools enabling specific intervention in, and recording of, cholinergic transmission. Here, we review the organization of septohippocampal cholinergic projections and hippocampal acetylcholine receptors as well as the role of cholinergic transmission in modulating cellular excitability, synaptic plasticity, and rhythmic network oscillations. We point to a number of open questions that remain unanswered and discuss the potential for recently developed techniques to provide a radical reappraisal of the function of cholinergic inputs to the hippocampus.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 340 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 4 1%
Netherlands 2 <1%
Australia 2 <1%
United States 2 <1%
Chile 1 <1%
Czechia 1 <1%
Germany 1 <1%
Japan 1 <1%
Brazil 1 <1%
Other 0 0%
Unknown 325 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 85 25%
Researcher 77 23%
Student > Master 36 11%
Student > Doctoral Student 22 6%
Student > Bachelor 20 6%
Other 52 15%
Unknown 48 14%
Readers by discipline Count As %
Neuroscience 115 34%
Agricultural and Biological Sciences 91 27%
Medicine and Dentistry 21 6%
Biochemistry, Genetics and Molecular Biology 19 6%
Psychology 17 5%
Other 18 5%
Unknown 59 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 April 2023.
All research outputs
#14,725,123
of 23,578,918 outputs
Outputs from Frontiers in Synaptic Neuroscience
#254
of 428 outputs
Outputs of similar age
#171,767
of 284,672 outputs
Outputs of similar age from Frontiers in Synaptic Neuroscience
#3
of 8 outputs
Altmetric has tracked 23,578,918 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 428 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one is in the 37th percentile – i.e., 37% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 284,672 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.