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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Function and Dysfunction of Microglia during Brain Development: Consequences for Synapses and Neural Circuits
|
|---|---|
| Published in |
Frontiers in Synaptic Neuroscience, May 2017
|
| DOI | 10.3389/fnsyn.2017.00009 |
| Pubmed ID | |
| Authors |
Rosa C. Paolicelli, Maria T. Ferretti |
| Abstract |
Many diverse factors, ranging from stress to infections, can perturb brain homeostasis and alter the physiological activity of microglia, the immune cells of the central nervous system. Microglia play critical roles in the process of synaptic maturation and brain wiring during development. Any perturbation affecting microglial physiological function during critical developmental periods could result in defective maturation of synaptic circuits. In this review, we critically appraise the recent literature on the alterations of microglial activity induced by environmental and genetic factors occurring at pre- and early post-natal stages. Furthermore, we discuss the long-lasting consequences of early-life microglial perturbation on synaptic function and on vulnerability to neurodevelopmental and psychiatric disorders. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Mexico | 1 | 6% |
| United States | 1 | 6% |
| Unknown | 14 | 88% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 9 | 56% |
| Scientists | 5 | 31% |
| Practitioners (doctors, other healthcare professionals) | 1 | 6% |
| Science communicators (journalists, bloggers, editors) | 1 | 6% |
Mendeley readers
The data shown below were compiled from readership statistics for 296 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1 | <1% |
| France | 1 | <1% |
| Unknown | 294 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 63 | 21% |
| Student > Bachelor | 38 | 13% |
| Researcher | 35 | 12% |
| Student > Master | 31 | 10% |
| Student > Doctoral Student | 19 | 6% |
| Other | 36 | 12% |
| Unknown | 74 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 92 | 31% |
| Biochemistry, Genetics and Molecular Biology | 39 | 13% |
| Agricultural and Biological Sciences | 35 | 12% |
| Medicine and Dentistry | 21 | 7% |
| Psychology | 8 | 3% |
| Other | 18 | 6% |
| Unknown | 83 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 October 2017.
All research outputs
#4,854,132
of 26,522,772 outputs
Outputs from Frontiers in Synaptic Neuroscience
#88
of 447 outputs
Outputs of similar age
#75,310
of 330,122 outputs
Outputs of similar age from Frontiers in Synaptic Neuroscience
#2
of 5 outputs
Altmetric has tracked 26,522,772 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 447 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.9. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 330,122 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 77% of its contemporaries.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.