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Evaluation of Pattern Recognition and Feature Extraction Methods in ADHD Prediction

Overview of attention for article published in Frontiers in Systems Neuroscience, January 2012
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Title
Evaluation of Pattern Recognition and Feature Extraction Methods in ADHD Prediction
Published in
Frontiers in Systems Neuroscience, January 2012
DOI 10.3389/fnsys.2012.00068
Pubmed ID
Authors

João Ricardo Sato, Marcelo Queiroz Hoexter, André Fujita, Luis Augusto Rohde

Abstract

Attention Deficit/Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder, being one of the most prevalent psychiatric disorders in childhood. The neural substrates associated with this condition, both from structural and functional perspectives, are not yet well established. Recent studies have highlighted the relevance of neuroimaging not only to provide a more solid understanding about the disorder but also for possible clinical support. The ADHD-200 Consortium organized the ADHD-200 global competition making publicly available, hundreds of structural magnetic resonance imaging (MRI) and functional MRI (fMRI) datasets of both ADHD patients and typically developing (TD) controls for research use. In the current study, we evaluate the predictive power of a set of three different feature extraction methods and 10 different pattern recognition methods. The features tested were regional homogeneity (ReHo), amplitude of low frequency fluctuations (ALFF), and independent components analysis maps (resting state networks; RSN). Our findings suggest that the combination ALFF+ReHo maps contain relevant information to discriminate ADHD patients from TD controls, but with limited accuracy. All classifiers provided almost the same performance in this case. In addition, the combination ALFF+ReHo+RSN was relevant in combined vs. inattentive ADHD classification, achieving a score accuracy of 67%. In this latter case, the performances of the classifiers were not equivalent and L2-regularized logistic regression (both in primal and dual space) provided the most accurate predictions. The analysis of brain regions containing most discriminative information suggested that in both classifications (ADHD vs. TD controls and combined vs. inattentive), the relevant information is not confined only to a small set of regions but it is spatially distributed across the whole brain.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 125 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 2%
Brazil 1 <1%
Netherlands 1 <1%
China 1 <1%
Singapore 1 <1%
Unknown 118 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 29 23%
Student > Ph. D. Student 20 16%
Student > Master 15 12%
Student > Bachelor 11 9%
Professor 7 6%
Other 21 17%
Unknown 22 18%
Readers by discipline Count As %
Psychology 18 14%
Neuroscience 17 14%
Computer Science 16 13%
Engineering 13 10%
Medicine and Dentistry 11 9%
Other 20 16%
Unknown 30 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 September 2012.
All research outputs
#23,010,126
of 25,654,806 outputs
Outputs from Frontiers in Systems Neuroscience
#1,299
of 1,410 outputs
Outputs of similar age
#229,709
of 251,300 outputs
Outputs of similar age from Frontiers in Systems Neuroscience
#41
of 51 outputs
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