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Effect of Underlying Renal Disease on Nutritional and Metabolic Profile of Older Adults with Reduced Renal Function

Overview of attention for article published in Frontiers in Nutrition, March 2017
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Title
Effect of Underlying Renal Disease on Nutritional and Metabolic Profile of Older Adults with Reduced Renal Function
Published in
Frontiers in Nutrition, March 2017
DOI 10.3389/fnut.2017.00004
Pubmed ID
Authors

Silvia Lai, Maria Ida Amabile, Silvia Altieri, Daniela Mastroluca, Carlo Lai, Paola Aceto, Massimiliano Crudo, Anna Rita D’Angelo, Maurizio Muscaritoli, Alessio Molfino

Abstract

Chronic kidney disease is a common condition in the general population, particularly among older adults. Renal impairment is in turn associated with metabolic and nutritional derangements and with increased risk of cardiovascular disease. To compare the metabolic, nutritional, and cardiovascular impact of reduced kidney function between patients with and without known renal disease. We enrolled consecutive outpatients (age ≥65 years) with reduced renal function who were divided into two groups: Group A with history of renal disease and Group B with unknown renal disease. Metabolic and nutritional parameters, including involuntary body weight loss (BWL) in the previous 6 months, mineral metabolism, inflammatory indices, and left ventricular mass index (LVMI), were evaluated. A total of 76 patients were enrolled. Group A (n = 39, M: 24, F: 15) showed greater BWL with a significant reduction of 25-hydroxyvitamin D, transferrin, cholinesterase, albumin, and LVMI with respect to Group B (p < 0.01). Conversely, Group B (n = 37, M: 23, F: 14) showed significantly increased intact parathyroid hormone, total cholesterol, low-density lipoprotein, triglycerides, and C-reactive protein when compared to Group A (p < 0.05). The positive history of renal disease may negatively impact on several metabolic and nutritional parameters related to increased cardiovascular risk among older adults.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 9 100%

Demographic breakdown

Readers by professional status Count As %
Professor > Associate Professor 2 22%
Student > Bachelor 2 22%
Student > Postgraduate 1 11%
Student > Master 1 11%
Unknown 3 33%
Readers by discipline Count As %
Medicine and Dentistry 3 33%
Neuroscience 1 11%
Unknown 5 56%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 September 2017.
All research outputs
#17,883,247
of 22,959,818 outputs
Outputs from Frontiers in Nutrition
#2,795
of 4,591 outputs
Outputs of similar age
#239,053
of 333,987 outputs
Outputs of similar age from Frontiers in Nutrition
#10
of 11 outputs
Altmetric has tracked 22,959,818 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,591 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.8. This one is in the 33rd percentile – i.e., 33% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 333,987 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.