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Optimizing Processing Technology of Cornus officinalis: Based on Anti-Fibrotic Activity

Overview of attention for article published in Frontiers in Nutrition, May 2022
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Title
Optimizing Processing Technology of Cornus officinalis: Based on Anti-Fibrotic Activity
Published in
Frontiers in Nutrition, May 2022
DOI 10.3389/fnut.2022.807071
Pubmed ID
Authors

Xin Han, Chuan Ding, Yan Ning, QiYuan Shan, Minjie Niu, Hao Cai, Peng Xu, Gang Cao

Abstract

Cornus officinalis, a kind of edible herbal medicine, has been widely used in the protection of liver and kidney due to its medicinal and nutritional effect. Its anti-inflammatory, anti-tumor, and anti-oxidant activities can be enhanced by wine-steamed (WS) processing. Based on the activations of hepatic stellate cells-T6 (HSC-T6) and HK-2, our study used single-factor plus orthogonal design to investigate the anti-fibrosis of C. officinalis processed with steamed (S), high-pressure steamed (HPS), WS, high-pressure wine-steamed (HPWS), wine-dipped (WD), and wine-fried (WF). The chemical constituents in processed C. officinalis with higher anti-fibrotic activities were detected by ultra-high performance liquid chromatography coupled with hybrid triple quadrupole time-of-flight mass spectrometry (UHPLC-Q-TOF-MS/MS). Results showed that C. officinalis with HPWS significantly inhibited the activations of HSC-T6 and HK-2. Moreover, compounds in C. officinalis with HPWS were obtained via UHPLC-Q-TOF-MS/MS, indicating that 27 components were changed compared with raw C. officinalis. These results demonstrated that HPWS is the optimal processing technology for anti-fibrosis of C. officinalis.

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Mendeley readers

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The data shown below were compiled from readership statistics for 3 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 3 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 2 67%
Unknown 1 33%
Readers by discipline Count As %
Unknown 3 100%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 June 2022.
All research outputs
#19,371,568
of 23,979,422 outputs
Outputs from Frontiers in Nutrition
#3,553
of 5,518 outputs
Outputs of similar age
#319,675
of 446,185 outputs
Outputs of similar age from Frontiers in Nutrition
#421
of 676 outputs
Altmetric has tracked 23,979,422 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,518 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.1. This one is in the 25th percentile – i.e., 25% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 446,185 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 676 others from the same source and published within six weeks on either side of this one. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.