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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Modeling the Mechanics of Cancer: Effect of Changes in Cellular and Extra-Cellular Mechanical Properties
|
|---|---|
| Published in |
Frontiers in oncology, January 2013
|
| DOI | 10.3389/fonc.2013.00145 |
| Pubmed ID | |
| Authors |
Parag Katira, Roger T. Bonnecaze, Muhammad H. Zaman |
| Abstract |
Malignant transformation, though primarily driven by genetic mutations in cells, is also accompanied by specific changes in cellular and extra-cellular mechanical properties such as stiffness and adhesivity. As the transformed cells grow into tumors, they interact with their surroundings via physical contacts and the application of forces. These forces can lead to changes in the mechanical regulation of cell fate based on the mechanical properties of the cells and their surrounding environment. A comprehensive understanding of cancer progression requires the study of how specific changes in mechanical properties influences collective cell behavior during tumor growth and metastasis. Here we review some key results from computational models describing the effect of changes in cellular and extra-cellular mechanical properties and identify mechanistic pathways for cancer progression that can be targeted for the prediction, treatment, and prevention of cancer. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 195 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 2% |
| United Kingdom | 2 | 1% |
| France | 1 | <1% |
| Canada | 1 | <1% |
| Unknown | 187 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 55 | 28% |
| Researcher | 35 | 18% |
| Student > Master | 26 | 13% |
| Student > Bachelor | 18 | 9% |
| Student > Doctoral Student | 13 | 7% |
| Other | 25 | 13% |
| Unknown | 23 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Engineering | 51 | 26% |
| Agricultural and Biological Sciences | 30 | 15% |
| Biochemistry, Genetics and Molecular Biology | 24 | 12% |
| Physics and Astronomy | 21 | 11% |
| Chemical Engineering | 10 | 5% |
| Other | 33 | 17% |
| Unknown | 26 | 13% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 June 2013.
All research outputs
#22,938,588
of 25,576,801 outputs
Outputs from Frontiers in oncology
#16,170
of 22,703 outputs
Outputs of similar age
#259,377
of 289,927 outputs
Outputs of similar age from Frontiers in oncology
#193
of 328 outputs
Altmetric has tracked 25,576,801 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 22,703 research outputs from this source. They receive a mean Attention Score of 3.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 289,927 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 328 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.