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Toward a Molecular Classification of Colorectal Cancer: The Role of Microsatellite Instability Status

Overview of attention for article published in Frontiers in oncology, January 2013
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Title
Toward a Molecular Classification of Colorectal Cancer: The Role of Microsatellite Instability Status
Published in
Frontiers in oncology, January 2013
DOI 10.3389/fonc.2013.00272
Pubmed ID
Authors

Karl Heinimann

Abstract

Microsatellite instability (MSI) is the molecular hallmark of DNA mismatch repair deficiency. Since its initial description in colorectal cancer (CRC) in 1993 and its association with Lynch syndrome, the most common inherited cancer predisposition world-wide, accumulating evidence suggests that MSI status may also be of concrete prognostic and predictive value in the management of sporadic CRC. This mini review aims at providing a concise survey of the molecular basis and the multifaceted role(s) of MSI status in today's clinical practice.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 3%
United Kingdom 1 2%
Denmark 1 2%
Belgium 1 2%
Unknown 54 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 24%
Student > Bachelor 13 22%
Researcher 8 14%
Student > Master 8 14%
Student > Doctoral Student 3 5%
Other 7 12%
Unknown 6 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 27 46%
Medicine and Dentistry 19 32%
Biochemistry, Genetics and Molecular Biology 5 8%
Business, Management and Accounting 1 2%
Unknown 7 12%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 October 2013.
All research outputs
#22,759,452
of 25,373,627 outputs
Outputs from Frontiers in oncology
#15,917
of 22,416 outputs
Outputs of similar age
#258,412
of 288,991 outputs
Outputs of similar age from Frontiers in oncology
#194
of 328 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 22,416 research outputs from this source. They receive a mean Attention Score of 3.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 288,991 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 328 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.