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Burden of Cancers Attributable to Infectious Agents in Nigeria: 2012–2014

Overview of attention for article published in Frontiers in oncology, October 2016
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  • Above-average Attention Score compared to outputs of the same age (63rd percentile)
  • Good Attention Score compared to outputs of the same age and source (75th percentile)

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23 Dimensions

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109 Mendeley
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Title
Burden of Cancers Attributable to Infectious Agents in Nigeria: 2012–2014
Published in
Frontiers in oncology, October 2016
DOI 10.3389/fonc.2016.00216
Pubmed ID
Authors

Michael Odutola, Elima E. Jedy-Agba, Eileen O. Dareng, Emmanuel Aja Oga, Festus Igbinoba, Theresa Otu, Emmanuel Ezeome, Ramatu Hassan, Clement A. Adebamowo

Abstract

Infections by certain viruses, bacteria, and parasites have been identified as risk factors for some cancers. In Nigeria, like many other developing countries, infections remain a leading cause of morbidity and mortality. While there are data on the incidence of different cancers in Nigeria, there has been no study of cancers attributable to infections. This study was carried out to determine the burden of cancers attributable to infections using data from two population-based cancer registries (PBCRs) in Nigeria. We obtained data on cancers associated with EBV, human papillomavirus (HPV), hepatitis B and C, HIV, HHV8, Helicobacter pylori, and Schistosoma spp. from the databases of Abuja and Enugu cancer registries in Nigeria. We used population-attributable fraction for infections-associated cancers in developing countries that are based on prevalence data and relative risk estimates from previous studies. The PBCRs reported 4,336 incident cancer cases [age standardized incidence rate (ASR) 113.9 per 100,000] from 2012 to 2014, of which 1,627 (37.5%) were in males and 2,709 (62.5%) were in females. Some 1,030 (23.8%) of these cancers were associated with infections (ASR 44.4 per 100,000), while 951 (22.0%) were attributable to infections (ASR 41.6 per 100,000). Cancers of the cervix (n = 392, ASR 28.3 per 100,000) and liver (n = 145, ASR 3.4 per 100,000); and non-Hodgkin's lymphoma (n = 110, ASR 2.5 per 100,000) were the commonest infections-associated cancers overall. The commonest infectious agents associated with cancers in this population were HPV, EBV, hepatitis B and C, HIV, and HHV8. Our results suggest that 23.8% of incident cancer cases in this population were associated with infections, while 22.0% were attributable to infections. The infections attributable cancers are potentially preventable with strategies, such as vaccination, risk factor modification, or anti-infective treatment.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 109 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 <1%
United States 1 <1%
Kenya 1 <1%
Unknown 106 97%

Demographic breakdown

Readers by professional status Count As %
Student > Master 18 17%
Researcher 14 13%
Student > Ph. D. Student 14 13%
Other 8 7%
Student > Postgraduate 7 6%
Other 13 12%
Unknown 35 32%
Readers by discipline Count As %
Medicine and Dentistry 37 34%
Immunology and Microbiology 8 7%
Biochemistry, Genetics and Molecular Biology 7 6%
Nursing and Health Professions 6 6%
Agricultural and Biological Sciences 3 3%
Other 8 7%
Unknown 40 37%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 February 2017.
All research outputs
#8,427,292
of 25,374,647 outputs
Outputs from Frontiers in oncology
#3,260
of 22,416 outputs
Outputs of similar age
#118,121
of 320,945 outputs
Outputs of similar age from Frontiers in oncology
#14
of 58 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one has received more attention than most of these and is in the 66th percentile.
So far Altmetric has tracked 22,416 research outputs from this source. They receive a mean Attention Score of 3.0. This one has done well, scoring higher than 85% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 320,945 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.
We're also able to compare this research output to 58 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.