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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Oncolytic Viruses—Interaction of Virus and Tumor Cells in the Battle to Eliminate Cancer
|
|---|---|
| Published in |
Frontiers in oncology, September 2017
|
| DOI | 10.3389/fonc.2017.00195 |
| Pubmed ID | |
| Authors |
Anwen Howells, Giulia Marelli, Nicholas R. Lemoine, Yaohe Wang |
| Abstract |
Oncolytic viruses (OVs) are an emerging treatment option for many cancer types and have recently been the focus of extensive research aiming to develop their therapeutic potential. The ultimate aim is to design a virus which can effectively replicate within the host, specifically target and lyse tumor cells and induce robust, long lasting tumor-specific immunity. There are a number of viruses which are either naturally tumor-selective or can be modified to specifically target and eliminate tumor cells. This means they are able to infect only tumor cells and healthy tissue remains unharmed. This specificity is imperative in order to reduce the side effects of oncolytic virotherapy. These viruses can also be modified by various methods including insertion and deletion of specific genes with the aim of improving their efficacy and safety profiles. In this review, we have provided an overview of the various virus species currently being investigated for their oncolytic potential and the positive and negative effects of a multitude of modifications used to increase their infectivity, anti-tumor immunity, and treatment safety, in particular focusing on the interaction of tumor cells and OVs. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 3 | 14% |
| Paraguay | 1 | 5% |
| Colombia | 1 | 5% |
| Unknown | 17 | 77% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 19 | 86% |
| Scientists | 2 | 9% |
| Practitioners (doctors, other healthcare professionals) | 1 | 5% |
Mendeley readers
The data shown below were compiled from readership statistics for 220 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 220 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 59 | 27% |
| Student > Master | 30 | 14% |
| Researcher | 21 | 10% |
| Student > Ph. D. Student | 20 | 9% |
| Student > Doctoral Student | 8 | 4% |
| Other | 19 | 9% |
| Unknown | 63 | 29% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 62 | 28% |
| Agricultural and Biological Sciences | 25 | 11% |
| Immunology and Microbiology | 24 | 11% |
| Medicine and Dentistry | 16 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 9 | 4% |
| Other | 14 | 6% |
| Unknown | 70 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 43. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 November 2022.
All research outputs
#1,009,924
of 26,415,653 outputs
Outputs from Frontiers in oncology
#175
of 23,127 outputs
Outputs of similar age
#19,632
of 328,862 outputs
Outputs of similar age from Frontiers in oncology
#3
of 92 outputs
Altmetric has tracked 26,415,653 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 23,127 research outputs from this source. They receive a mean Attention Score of 3.2. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 328,862 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 92 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.