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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Prognostic Value of the Number of Removed Lymph Nodes in Vulvar Squamous Cell Carcinoma Patients With Node-Positive Disease: A Population-Based Study
|
|---|---|
| Published in |
Frontiers in oncology, May 2018
|
| DOI | 10.3389/fonc.2018.00184 |
| Pubmed ID | |
| Authors |
San-Gang Wu, Wen-Wen Zhang, Jia-Yuan Sun, Qiong-Hua Chen, Zhen-Yu He, Juan Zhou |
| Abstract |
To investigate the effect of the number of removed lymph nodes (RLNs) on outcomes in patients with node-positive vulvar squamous cell carcinoma (SCC). This population-based retrospective study included vulvar SCC patients recorded on the surveillance, epidemiology, and end results database, who received surgery and lymphadenectomy. Cox regression proportional hazards were used for multivariate analysis. The number of RLNs was examined as a 4-level categorical variable based on quartiles. In total, 703 patients were identified. Patients with a higher RLN count had a significantly higher number of positive lymph nodes. The 3-year cause-specific survival (CSS) rates were 48.9, 65.9, 73.1, and 67.3% in patients with 1-6, 7-10, 11-16, and 17-45 RLNs, respectively (p < 0.001), and the 3-year overall survival (OS) rates were 36.1, 50.6, 61.1, and 57.6%, for the same RLN groups, respectively (p < 0.001). RLN count was an independent predictor of outcome. Using 7-10 RLNs as reference, patients with 1-6 RLNs had poor CSS [hazard ratio (HR) 1.727, 95% confidence interval (CI) 1.201-2.485, p = 0.003] and OS (HR 1.436, 95% CI 1.078-1.911, p = 0.013), while there were comparable outcomes in patients with 11-16 and 17-45 RLNs to patients with 7-10 RLNs. Adjuvant radiotherapy improved CSS (p = 0.023) and OS (p = 0.003) in patients with ≤6 RLNs, but was not associated with better outcomes in patients with >6 RLNs. The removal of more than six lymph nodes improves vulvar SCC outcomes in patients with node-positive disease. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 6 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 6 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 2 | 33% |
| Professor > Associate Professor | 1 | 17% |
| Researcher | 1 | 17% |
| Other | 1 | 17% |
| Unknown | 1 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 2 | 33% |
| Chemistry | 1 | 17% |
| Unknown | 3 | 50% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 May 2018.
All research outputs
#22,905,350
of 25,540,105 outputs
Outputs from Frontiers in oncology
#16,130
of 22,658 outputs
Outputs of similar age
#302,813
of 344,671 outputs
Outputs of similar age from Frontiers in oncology
#119
of 154 outputs
Altmetric has tracked 25,540,105 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 22,658 research outputs from this source. They receive a mean Attention Score of 3.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 154 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.