Title |
Long-term Outcomes of Childhood Onset Nephrotic Syndrome
|
---|---|
Published in |
Frontiers in Pediatrics, May 2016
|
DOI | 10.3389/fped.2016.00053 |
Pubmed ID | |
Authors |
Rebecca Hjorten, Zohra Anwar, Kimberly Jean Reidy |
Abstract |
There are limited studies on long-term outcomes of childhood onset nephrotic syndrome (NS). A majority of children with NS have steroid-sensitive nephrotic syndrome (SSNS). Steroid-resistant nephrotic syndrome (SRNS) is associated with a high risk of developing end-stage renal disease. Biomarkers and analysis of genetic mutations may provide new information for prognosis in SRNS. Frequently relapsing and steroid-dependent NS is associated with long-term complications, including dyslipidemia, cataracts, osteoporosis and fractures, obesity, impaired growth, and infertility. Long-term complications of SSNS are likely to be under-recognized. There remain many gaps in our knowledge of long-term outcomes of childhood NS, and further study is indicated. |
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Geographical breakdown
Country | Count | As % |
---|---|---|
Turkey | 1 | 17% |
Venezuela, Bolivarian Republic of | 1 | 17% |
Switzerland | 1 | 17% |
Unknown | 3 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 5 | 83% |
Science communicators (journalists, bloggers, editors) | 1 | 17% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 65 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Postgraduate | 9 | 14% |
Student > Bachelor | 9 | 14% |
Student > Master | 8 | 12% |
Student > Ph. D. Student | 6 | 9% |
Researcher | 5 | 8% |
Other | 15 | 23% |
Unknown | 13 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 38 | 58% |
Agricultural and Biological Sciences | 3 | 5% |
Biochemistry, Genetics and Molecular Biology | 2 | 3% |
Nursing and Health Professions | 2 | 3% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 2% |
Other | 3 | 5% |
Unknown | 16 | 25% |