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Up, Down, and All Around: Diagnosis and Treatment of Novel STAT3 Variant

Overview of attention for article published in Frontiers in Pediatrics, March 2017
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  • Average Attention Score compared to outputs of the same age
  • Above-average Attention Score compared to outputs of the same age and source (55th percentile)

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2 X users
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Citations

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25 Dimensions

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22 Mendeley
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Title
Up, Down, and All Around: Diagnosis and Treatment of Novel STAT3 Variant
Published in
Frontiers in Pediatrics, March 2017
DOI 10.3389/fped.2017.00049
Pubmed ID
Authors

Michael Alexander Weinreich, Tiphanie P. Vogel, V. Koneti Rao, Joshua D. Milner

Abstract

The number of identified monogenic causes of childhood-onset autoimmunity due to nodal and extranodal lymphoproliferation has increased. These pathogenic genetic variants provide the potential for pathway-specific treatment. Novel variants also require pathway-specific verification. In this report, we describe a 14-year-old patient with a novel variant in STAT3. We report clinical and laboratory findings that support STAT3 p.G419R as a novel pathogenic STAT3 gain-of-function variant.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 22 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 32%
Other 3 14%
Student > Ph. D. Student 3 14%
Student > Master 2 9%
Lecturer 1 5%
Other 1 5%
Unknown 5 23%
Readers by discipline Count As %
Medicine and Dentistry 6 27%
Immunology and Microbiology 6 27%
Biochemistry, Genetics and Molecular Biology 3 14%
Agricultural and Biological Sciences 1 5%
Unknown 6 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 April 2018.
All research outputs
#13,436,587
of 23,198,445 outputs
Outputs from Frontiers in Pediatrics
#1,682
of 6,207 outputs
Outputs of similar age
#156,054
of 308,957 outputs
Outputs of similar age from Frontiers in Pediatrics
#32
of 79 outputs
Altmetric has tracked 23,198,445 research outputs across all sources so far. This one is in the 41st percentile – i.e., 41% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,207 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 308,957 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 79 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.