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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Group B Streptococcal Maternal Colonization and Neonatal Disease: Molecular Mechanisms and Preventative Approaches
|
|---|---|
| Published in |
Frontiers in Pediatrics, February 2018
|
| DOI | 10.3389/fped.2018.00027 |
| Pubmed ID | |
| Authors |
Kathryn A. Patras, Victor Nizet |
| Abstract |
Group BStreptococcus(GBS) colonizes the gastrointestinal and vaginal epithelium of a significant percentage of healthy women, with potential for ascending intrauterine infection or transmission during parturition, creating a risk of serious disease in the vulnerable newborn. This review highlights new insights on the bacterial virulence determinants, host immune responses, and microbiome interactions that underpin GBS vaginal colonization, the proximal step in newborn infectious disease pathogenesis. From the pathogen perspective, the function GBS adhesins and biofilms, β-hemolysin/cytolysin toxin, immune resistance factors, sialic acid mimicry, and two-component transcriptional regulatory systems are reviewed. From the host standpoint, pathogen recognition, cytokine responses, and the vaginal mucosal and placental immunity to the pathogen are detailed. Finally, the rationale, efficacy, and potential unintended consequences of current universal recommended intrapartum antibiotic prophylaxis are considered, with updates on new developments toward a GBS vaccine or alternative approaches to reducing vaginal colonization. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 22% |
| United Kingdom | 1 | 11% |
| Switzerland | 1 | 11% |
| Chile | 1 | 11% |
| Unknown | 4 | 44% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 56% |
| Scientists | 3 | 33% |
| Science communicators (journalists, bloggers, editors) | 1 | 11% |
Mendeley readers
The data shown below were compiled from readership statistics for 269 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 269 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 38 | 14% |
| Researcher | 26 | 10% |
| Student > Ph. D. Student | 26 | 10% |
| Student > Bachelor | 25 | 9% |
| Student > Postgraduate | 17 | 6% |
| Other | 48 | 18% |
| Unknown | 89 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 50 | 19% |
| Biochemistry, Genetics and Molecular Biology | 33 | 12% |
| Immunology and Microbiology | 30 | 11% |
| Nursing and Health Professions | 19 | 7% |
| Agricultural and Biological Sciences | 15 | 6% |
| Other | 30 | 11% |
| Unknown | 92 | 34% |
Attention Score in Context
This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 August 2021.
All research outputs
#2,089,173
of 23,023,224 outputs
Outputs from Frontiers in Pediatrics
#317
of 6,096 outputs
Outputs of similar age
#47,404
of 330,913 outputs
Outputs of similar age from Frontiers in Pediatrics
#11
of 97 outputs
Altmetric has tracked 23,023,224 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,096 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.6. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 330,913 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 97 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.