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Short- and Long-Term Renal Outcome of Hemolytic-Uremic Syndrome in Childhood

Overview of attention for article published in Frontiers in Pediatrics, August 2018
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  • Good Attention Score compared to outputs of the same age (70th percentile)
  • Good Attention Score compared to outputs of the same age and source (68th percentile)

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Title
Short- and Long-Term Renal Outcome of Hemolytic-Uremic Syndrome in Childhood
Published in
Frontiers in Pediatrics, August 2018
DOI 10.3389/fped.2018.00220
Pubmed ID
Authors

Laura Vaterodt, Johannes Holle, Dieter Hüseman, Dominik Müller, Julia Thumfart

Abstract

Introduction: Hemolytic-uremic syndrome (HUS) is a common cause for intrarenal acute kidney injury in childhood. More than 90% of HUS cases are associated with an infection by Shigatoxin-producing Escherichia coli (STEC) whereas the reminder comprises a heterogeneous group (here classified as Non-STEC-HUS). Renal impairment can persist in patients with HUS. This study presents data from four decades investigating the short- and long-term outcome of HUS in childhood. Materials and Methods: In a retrospective single-center-study clinical and laboratory data of the acute phase and of 1- to 10-year follow-up visits of children with HUS were analyzed. Results: 92 HUS-patients were identified from 1996 to 2014 (STEC-HUS-group: n = 76; Non-STEC-HUS-group: n = 16) and 220 HUS-patients between 1976 and 1995. STEC-HUS was increasingly caused by Non-O157 strains and mortality rate declined over the past decades (1.3 vs. 9.5%). Renal sequelae persisted more often in the group 1976-1995 (39.3%) than in the group 1996-2014 (28.3%), but more than 50% of all patients were lost to follow-up. Conclusion: Although renal outcome has improved over the investigated last decades, patients with HUS still face a high risk of permanent renal damage. These findings underline the importance of a consequent long-term follow-up in HUS-patients.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 21 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 24%
Student > Doctoral Student 3 14%
Student > Master 3 14%
Lecturer 1 5%
Student > Ph. D. Student 1 5%
Other 3 14%
Unknown 5 24%
Readers by discipline Count As %
Medicine and Dentistry 11 52%
Biochemistry, Genetics and Molecular Biology 2 10%
Veterinary Science and Veterinary Medicine 1 5%
Nursing and Health Professions 1 5%
Chemistry 1 5%
Other 0 0%
Unknown 5 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 October 2019.
All research outputs
#5,896,546
of 23,622,736 outputs
Outputs from Frontiers in Pediatrics
#981
of 6,527 outputs
Outputs of similar age
#98,844
of 331,600 outputs
Outputs of similar age from Frontiers in Pediatrics
#24
of 74 outputs
Altmetric has tracked 23,622,736 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 6,527 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 331,600 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.
We're also able to compare this research output to 74 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.