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Chemotherapy-induced peripheral neurotoxicity and complementary and alternative medicines: progress and perspective

Overview of attention for article published in Frontiers in Pharmacology, October 2015
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Title
Chemotherapy-induced peripheral neurotoxicity and complementary and alternative medicines: progress and perspective
Published in
Frontiers in Pharmacology, October 2015
DOI 10.3389/fphar.2015.00234
Pubmed ID
Authors

Xiao L. Cheng, Hong Q. Liu, Qi Wang, Jie G. Huo, Xiao N. Wang, Peng Cao

Abstract

Chemotherapy-induced peripheral neurotoxicity (CIPN) is a severe and dose-limiting side effect of antineoplastic drugs. It can cause sensory, motor and autonomic system dysfunction, and ultimately force patients to discontinue chemotherapy. Until now, little is understood about CIPN and no consistent caring standard is available. Since CIPN is a multifactorial disease, the clinical efficacy of single pharmacological drugs is disappointing, prompting patients to seek alternative treatment options. Complementary and alternative medicines (CAMs), especially herbal medicines, are well known for their multifaceted implications and widely used in human health care. Up to date, several phytochemicals, plant extractions, and herbal formulas have been evaluated for their potential therapeutic benefit of preventing the onset and progression of CIPN in experimental models. Clinical acupuncture has also been shown to improve CIPN symptoms. In this review, we will give an outline of our current knowledge regrading the advanced research of CIPN, the role of CAMs in alleviating CIPN and possible lacunae in research that needs to be addressed.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 64 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 64 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 13%
Student > Master 8 13%
Student > Bachelor 7 11%
Professor > Associate Professor 4 6%
Student > Doctoral Student 3 5%
Other 11 17%
Unknown 23 36%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 12 19%
Medicine and Dentistry 11 17%
Neuroscience 4 6%
Nursing and Health Professions 4 6%
Agricultural and Biological Sciences 2 3%
Other 7 11%
Unknown 24 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 October 2015.
All research outputs
#20,294,248
of 22,830,751 outputs
Outputs from Frontiers in Pharmacology
#10,066
of 16,070 outputs
Outputs of similar age
#237,866
of 283,600 outputs
Outputs of similar age from Frontiers in Pharmacology
#77
of 96 outputs
Altmetric has tracked 22,830,751 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 16,070 research outputs from this source. They receive a mean Attention Score of 4.9. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 283,600 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 96 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.