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Extracted Triterpenes from Antrodia cinnamomea Reduce the Inflammation to Promote the Wound Healing via the STZ Inducing Hyperglycemia-Diabetes Mice Model

Overview of attention for article published in Frontiers in Pharmacology, June 2016
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Title
Extracted Triterpenes from Antrodia cinnamomea Reduce the Inflammation to Promote the Wound Healing via the STZ Inducing Hyperglycemia-Diabetes Mice Model
Published in
Frontiers in Pharmacology, June 2016
DOI 10.3389/fphar.2016.00154
Pubmed ID
Authors

Yu-Sheng Wu, Shiu-Nan Chen

Abstract

This research evaluated the effects of triterpenes on the regulation of STZ-induced hyperglycaemic diabetes through an anti-inflammatory response. Diabetic mice were orally administered various concentrations of triterpenes on a daily basis. Weight gain, volume of drinking water, and liver and spleen weight were recorded and evaluated. These evaluations presented a positive regulation to the abnormal metabolism appearance compared to the diabetic mice. In the diabetic mice, the detection of adiponectin production or elevated levels of inflammatory factors such as CCL1 and TPO expression were found to reduce hyperglycaemia and thereby induce an inflammatory response. Moreover, to the best of our knowledge, hyperglycaemia impairs the tissue healing associated with an increased and prolonged inflammatory response. An investigation of the anti-inflammatory response in wound healing as affected by the triterpenes verified the promotion of wound recovery.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 29 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 29 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 17%
Professor > Associate Professor 4 14%
Student > Bachelor 3 10%
Student > Doctoral Student 2 7%
Student > Ph. D. Student 2 7%
Other 4 14%
Unknown 9 31%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 4 14%
Medicine and Dentistry 3 10%
Nursing and Health Professions 3 10%
Pharmacology, Toxicology and Pharmaceutical Science 2 7%
Unspecified 1 3%
Other 5 17%
Unknown 11 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 June 2016.
All research outputs
#20,333,181
of 22,877,793 outputs
Outputs from Frontiers in Pharmacology
#10,115
of 16,169 outputs
Outputs of similar age
#305,071
of 352,763 outputs
Outputs of similar age from Frontiers in Pharmacology
#74
of 116 outputs
Altmetric has tracked 22,877,793 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 16,169 research outputs from this source. They receive a mean Attention Score of 4.9. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 116 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.