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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Nanomedicine-Mediated Therapies to Target Breast Cancer Stem Cells
|
|---|---|
| Published in |
Frontiers in Pharmacology, September 2016
|
| DOI | 10.3389/fphar.2016.00313 |
| Pubmed ID | |
| Authors |
Lili He, Jian Gu, Lee Y. Lim, Zhi-xiang Yuan, Jingxin Mo |
| Abstract |
Accumulating evidences have suggested the existence of breast cancer stem cells (BCSCs), which possess the potential of both self-renewal and differentiation. The origin of BCSCs might have relationship to the development of normal mammary stem cells. BCSCs are believed to play a key role in the initiation, recurrence and chemo-/radiotherapy resistances of breast cancer. Therefore, elimination of BCSCs is crucial for breast cancer therapy. However, conventional chemo and radiation therapies cannot eradicate BCSCs effectively. Fortunately, nanotechnology holds great potential for specific and efficient anti-BCSCs treatment. "Smart" nanocarriers can distinguish BCSCs from the other breast cancer cells and selectively deliver therapeutic agents to the BCSCs. Emerging findings suggest that BCSCs in breast cancer could be successfully inhibited and even eradicated by functionalized nanomedicines. In this review, we focus on origin of BCSCs, strategies used to target BCSCs, and summarize the nanotechnology-based delivery systems that have been applied for eliminating BCSCs in breast cancer. |
X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 4 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Scientists | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 170 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 170 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 41 | 24% |
| Student > Ph. D. Student | 24 | 14% |
| Student > Master | 18 | 11% |
| Researcher | 12 | 7% |
| Student > Postgraduate | 5 | 3% |
| Other | 10 | 6% |
| Unknown | 60 | 35% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 43 | 25% |
| Pharmacology, Toxicology and Pharmaceutical Science | 20 | 12% |
| Agricultural and Biological Sciences | 12 | 7% |
| Medicine and Dentistry | 9 | 5% |
| Engineering | 4 | 2% |
| Other | 16 | 9% |
| Unknown | 66 | 39% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 October 2016.
All research outputs
#13,785,838
of 22,888,307 outputs
Outputs from Frontiers in Pharmacology
#4,286
of 16,185 outputs
Outputs of similar age
#174,862
of 322,146 outputs
Outputs of similar age from Frontiers in Pharmacology
#62
of 167 outputs
Altmetric has tracked 22,888,307 research outputs across all sources so far. This one is in the 38th percentile – i.e., 38% of other outputs scored the same or lower than it.
So far Altmetric has tracked 16,185 research outputs from this source. They receive a mean Attention Score of 4.9. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 322,146 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 167 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 62% of its contemporaries.