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The Market of Biopharmaceutical Medicines: A Snapshot of a Diverse Industrial Landscape

Overview of attention for article published in Frontiers in Pharmacology, June 2017
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  • Above-average Attention Score compared to outputs of the same age and source (63rd percentile)

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Title
The Market of Biopharmaceutical Medicines: A Snapshot of a Diverse Industrial Landscape
Published in
Frontiers in Pharmacology, June 2017
DOI 10.3389/fphar.2017.00314
Pubmed ID
Authors

Evelien Moorkens, Nicolas Meuwissen, Isabelle Huys, Paul Declerck, Arnold G. Vulto, Steven Simoens

Abstract

Background: Biopharmaceutical medicines represent a growing share of the global pharmaceutical market, and with many of these biopharmaceutical products facing loss of exclusivity rights, also biosimilars may now enter the biopharmaceutical market. Objectives: This study aims to identify and document which investment and development strategies are adopted by industrial players in the global biopharmaceutical market. Methods: A descriptive analysis was undertaken of the investment and development strategies of the top 25 pharmaceutical companies according to 2015 worldwide prescription drug sales. Strategies were documented by collecting data on manufacturing plans, development programs, acquisition and collaboration agreements, the portfolio and pipeline of biosimilar, originator and next-generation biopharmaceutical products. Data were extracted from publicly available sources. Results: Various investment and development strategies can be identified in the global biopharmaceutical market: (a) development of originator biopharmaceuticals, (b) investment in biotechnology, (c) development of next-generation biopharmaceuticals, (d) development of biosimilars, (e) investment in emerging countries, and (f) collaboration between companies. In the top 25 pharmaceutical companies almost every company invests in originator biopharmaceuticals and in biotechnology in general, but only half of them develops next-generation biopharmaceuticals. Furthermore, only half of them invest in development of biosimilars. The companies' biosimilar pipeline is mainly focused on development of biosimilar monoclonal antibodies and to some extent on biosimilar insulins. A common strategy is collaboration between companies and investment in emerging countries. Conclusions: A snapshot of investment and development strategies used by industrial players in the global biopharmaceutical market shows that all top 25 pharmaceutical companies are engaged in the biopharmaceutical market and that this industrial landscape is diverse. Companies do not focus on a single strategy, but are involved in multiple investment and development strategies. A common strategy to market biopharmaceuticals is collaboration between companies. These collaborations can as well be used to gain access in regions the company has less experience with. With patents expiring for some of the highest selling monoclonal antibodies, this snapshot highlights the interest of companies to invest in the development of these molecules and/or enter into collaborations to create access to these molecules.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 297 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 297 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 53 18%
Student > Master 50 17%
Student > Ph. D. Student 45 15%
Student > Doctoral Student 25 8%
Researcher 24 8%
Other 25 8%
Unknown 75 25%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 58 20%
Pharmacology, Toxicology and Pharmaceutical Science 43 14%
Agricultural and Biological Sciences 29 10%
Chemical Engineering 23 8%
Engineering 16 5%
Other 49 16%
Unknown 79 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 October 2022.
All research outputs
#14,683,641
of 23,509,982 outputs
Outputs from Frontiers in Pharmacology
#4,962
of 17,081 outputs
Outputs of similar age
#178,522
of 318,412 outputs
Outputs of similar age from Frontiers in Pharmacology
#89
of 260 outputs
Altmetric has tracked 23,509,982 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 17,081 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.0. This one has gotten more attention than average, scoring higher than 68% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 318,412 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 260 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.